Evidence map›Paper›PMID 33298570›Full record

ArticleBiology open2021

Establishment of

Xianyu Zhang, Xin Zhao, Guoling Li, Mao Zhang, Pingping Xing, Zicong Li, Bin Chen, Huaqiang Yang, Zhenfang Wu

Open access · goldAbstract read
In one paragraph

Article in Biology open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Male germ cell technologies in large animals.The Journal of reproduction and development · 2026
    Review
  3. Review
  4. eNeuro · 2025
    Article
  5. Article
  6. ETS Transcription Factors in Immune Cells and Immune-Related Diseases.International journal of molecular sciences · 2024
    Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Xianyu ZhangCollege of Animal Science and Technology, Hunan Agricultural University, Changsha, Hunan 410128, China.ORCID 0000-0003-4071-6057
Xin ZhaoNational Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangzhou 510642, China.ORCID 0000-0003-2888-3573
Guoling LiNational Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangzhou 510642, China.ORCID 0000-0003-0422-6157
Mao ZhangNational Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangzhou 510642, China.ORCID 0000-0002-4916-1193
Pingping XingNational Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangzhou 510642, China.ORCID 0000-0003-4807-225X
Zicong LiNational Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangzhou 510642, China.
Bin ChenCollege of Animal Science and Technology, Hunan Agricultural University, Changsha, Hunan 410128, China yangh@scau.edu.cn chenbin7586@126.com wzf@scau.edu.cn.ORCID 0000-0002-2320-2452
Huaqiang YangNational Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangzhou 510642, China yangh@scau.edu.cn chenbin7586@126.com wzf@scau.edu.cn.ORCID 0000-0002-4287-0026
Zhenfang WuNational Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangzhou 510642, China yangh@scau.edu.cn chenbin7586@126.com wzf@scau.edu.cn.ORCID 0000-0002-5586-6771
South China Agricultural University · CNHunan Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spermatogonial stem cell (SSC) transplantation is an alternative reproductive method to achieve conservation and production of elite animals in livestock production. Creating a recipient animal without endogenous germ cells is important for effective SSC transplantation. However, natural mutants with depletion of SSCs are difficult to obtain, and drug ablation of endogenous germ cells is arduous to perform for practical use. In this study, we used mouse models to study the preparation of recipients with congenital germ cell ablation. We knocked out (KO) Ets-variant gene 5 (

Indexed as

Mice, KnockoutModels, AnimalStem Cell TransplantationAdult Germline Stem CellsAllelesAnimalsCRISPR-Cas SystemsDNA-Binding ProteinsGene EditingGenotypeMiceTranscription FactorsTransplantation, HomologousDNA-Binding ProteinsEtv5 protein, mouseTranscription FactorsEtv5Gene knockoutSpermatogenesisSpermatogonial stem cellsTransplantation

Identifiers

PMID33298570
PMCPMC7803462
OpenAlexW3111745526

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.