Evidence map›Paper›PMID 33298546›Full record

ArticleJournal of virology2021

Expression of HIV-1 Intron-Containing RNA in Microglia Induces Inflammatory Responses.

Hisashi Akiyama, Sallieu Jalloh, Seonmi Park, Maohua Lei, Gustavo Mostoslavsky, Suryaram Gummuluru

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hisashi AkiyamaDepartment of Microbiology, Center for Regenerative Medicine (CReM), Boston University School of Medicine, Boston MA 02118 hakiyama@bu.edu.ORCID https://orcid.org/0000-0001-9228-0465
Sallieu JallohDepartment of Microbiology, Center for Regenerative Medicine (CReM), Boston University School of Medicine, Boston MA 02118.
Seonmi ParkDepartment of Microbiology, Center for Regenerative Medicine (CReM), Boston University School of Medicine, Boston MA 02118.
Maohua LeiDepartment of Microbiology, Center for Regenerative Medicine (CReM), Boston University School of Medicine, Boston MA 02118.
Gustavo MostoslavskyDepartment of Microbiology, Center for Regenerative Medicine (CReM), Boston University School of Medicine, Boston MA 02118.
Suryaram GummuluruDepartment of Microbiology, Center for Regenerative Medicine (CReM), Boston University School of Medicine, Boston MA 02118 rgummulu@bu.edu.ORCID https://orcid.org/0000-0002-8606-8481
Boston University · US

Funding

Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI CURT G BECKWITH · 1998 to 2026
$51.7M
Mechanism of cell-associated HIV-1 transmissionR01AI064099 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI GUMMULURU, SURYARAM · 2005 to 2020
$5.9M
Persistent HIV expression induced type I IFN responses and inflammagingR01AG060890 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI GUMMULURU, SURYARAM, LIN, NINA H. · 2018 to 2022
$3.8M
Synergistic Mechanisms of chronic Innate Immune Activation in Microglia by Opiates and HIV InfectionR01DA051889 · NIDA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI CHENG, CHRISTINE, GUMMULURU, SURYARAM · 2020 to 2024
$3.5M
Engineering a 3D human neurovascular unit for investigating and countering neuroinflammatory mechanisms of HIVR21NS105837 · NINDS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI GUMMULURU, SURYARAM, PORTER, TYRONE · 2017 to 2018
$474k
NIAID NIH HHS P30 AI042853NIAID NIH HHS R01 AI064099NIA NIH HHS R01 AG060890NIDA NIH HHS R01 DA051889NINDS NIH HHS R21 NS105837
6 · The paper itself

Abstract

Chronic neuroinflammation is observed in HIV

Identifiers

PMID33298546
PMCPMC8092841
OpenAlexW3112884593

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.