ArticleBMJ case reports2020
Hepatic perivascular epithelioid cell tumours in children with tuberous sclerosis.
Article in BMJ case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- "Update on pediatric primary liver tumors".Virchows Archiv : an international journal of pathology · 2025Review
- Hepatic epithelioid angiomyolipoma is scattered and unsuitable for surgery: a case report.The Journal of international medical research · 2023Article
- Malignant perivascular epithelioid cell neoplasm in the liver: report of a pediatric case.Surgical case reports · 2021Article
- Orbital Perivascular Epithelioid Cell Tumor in a Case of Tuberous Sclerosis.Case reports in ophthalmologyArticle
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Authors and funding
4 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Perivascular epithelioid cell tumours are a novel histological description of mesenchymal tumours consisting of perivascular and epithelioid cells. Angiomyolipomas are one of the commoner types of this tumour group. They are typically associated with the inherited condition tuberous sclerosis (TS). In TS they are often seen arising in the kidneys and brain, although much more rarely can be seen in the liver. While usually thought of as benign tumours there is little evidence to predict whether they will progress to malignancy. Currently, there is no recommended best management strategy between resection and surveillance. We report two patients with TS seen in our centre with these described PEComa liver lesions histologically, however only one required a resection. On review of the literature, features such as increased size, rapid growth and vascular invasion would be concerning for possible malignant potential and therefore merit resection, as well as significant symptoms.
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