Evidence map›Paper›PMID 33298457›Full record

ArticleeNeuro

Subunit-Specific Photocontrol of Glycine Receptors by Azobenzene-Nitrazepam Photoswitcher.

Galyna Maleeva, Alba Nin-Hill, Karin Rustler, Elena Petukhova, Daria Ponomareva, Elvira Mukhametova, Alexandre Mj Gomila, Daniel Wutz, Mercedes Alfonso-Prieto, Burkhard König and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 6 countries.

Galyna MaleevaInstitut National de la Santé et de la Recherche Médicale, Institut de Neurosciences des Systèmes, Aix-Marseille University, Marseille 13005, France gmalieieva@ibecbarcelona.eu malfonsoprieto@gmail.com pbreges@gmail.com.ORCID 0000-0002-1379-1521
Alba Nin-HillDepartment of Inorganic and Organic Chemistry (Section of Organic Chemistry) and Institute of Theoretical Chemistry (IQTCUB), University of Barcelona, Barcelona 08028, Spain.ORCID 0000-0002-8670-9031
Karin RustlerInstitute of Organic Chemistry, University of Regensburg, Regensburg 93053, Germany.ORCID 0000-0001-6548-1333
Elena PetukhovaDepartment of Normal Physiology, Kazan State Medical University, Kazan 420012, Russia.ORCID 0000-0002-9100-815X
Daria PonomarevaDepartment of Normal Physiology, Kazan State Medical University, Kazan 420012, Russia.ORCID 0000-0002-2768-1665
Elvira MukhametovaInstitut National de la Santé et de la Recherche Médicale, Institut de Neurosciences des Systèmes, Aix-Marseille University, Marseille 13005, France.
Alexandre Mj GomilaInstitute for Bioengineering of Catalonia, The Barcelona Institute of Science and Technology, Barcelona 08028, Spain.ORCID 0000-0003-0867-6171
Daniel WutzInstitute of Organic Chemistry, University of Regensburg, Regensburg 93053, Germany.
Mercedes Alfonso-PrietoInstitute for Advanced Simulation IAS-5 and Institute of Neuroscience and Medicine INM-9, Computational Biomedicine, Forschungszentrum Jülich, Jülich 52425, Germany gmalieieva@ibecbarcelona.eu malfonsoprieto@gmail.com pbreges@gmail.com.ORCID 0000-0003-4509-4517
Burkhard KönigInstitute of Organic Chemistry, University of Regensburg, Regensburg 93053, Germany.ORCID 0000-0002-6131-4850
Pau GorostizaInstitute for Bioengineering of Catalonia, The Barcelona Institute of Science and Technology, Barcelona 08028, Spain.ORCID 0000-0002-7268-5577
Piotr BregestovskiInstitut National de la Santé et de la Recherche Médicale, Institut de Neurosciences des Systèmes, Aix-Marseille University, Marseille 13005, France gmalieieva@ibecbarcelona.eu malfonsoprieto@gmail.com pbreges@gmail.com.ORCID 0000-0003-2699-7825
Kazan State Medical University · RUUniversity of Regensburg · DEAix-Marseille Université · FRForschungszentrum Jülich · DEInstitució Catalana de Recerca i Estudis Avançats · ESInstitute of Organic Chemistry · HUKazan Federal University · RUShanghai Institute for Science of Science · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photopharmacology is a unique approach that through a combination of photochemistry methods and advanced life science techniques allows the study and control of specific biological processes, ranging from intracellular pathways to brain circuits. Recently, a first photochromic channel blocker of anion-selective GABA

Indexed as

NitrazepamReceptors, GlycineAnimalsAzo CompoundsMicePatch-Clamp TechniquesazobenzeneAzo CompoundsNitrazepamReceptors, Glycinebrain slicesglycine receptorshypoglossal motoneuronsmolecular modellingpatch-clampphotopharmacology

Identifiers

PMID33298457
PMCPMC7877471
OpenAlexW3111160237

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.