Evidence map›Paper›PMID 33298141›Full record

ReviewParasites & vectors2020

Human gnathostomiasis: a neglected food-borne zoonosis.

Guo-Hua Liu, Miao-Miao Sun, Hany M Elsheikha, Yi-Tian Fu, Hiromu Sugiyama, Katsuhiko Ando, Woon-Mok Sohn, Xing-Quan Zhu, Chaoqun Yao

Abstract readReview
In one paragraph

Review in Parasites & vectors, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. A Case of Creeping Disease Caused byClinical case reports · 2025
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  9. Two Patients With Angioedema and Persistent Lower Extremity Swelling.The journal of allergy and clinical immunology. In practice · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Helminth infection in wild boars in Primorye, Russia.International journal for parasitology. Parasites and wildlife · 2024
    Article
  14. Complete mitochondrial genome ofMicrobiology resource announcements · 2024
    Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Evaluation of the Anti-Antibiotics (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Guo-Hua LiuHunan Provincial Key Laboratory of Protein Engineering in Animal Vaccines, College of Veterinary Medicine, Hunan Agricultural University, Changsha, 410128, Hunan, People's Republic of China.
Miao-Miao SunState Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, 730046, Gansu, People's Republic of China.
Hany M ElsheikhaFaculty of Medicine and Health Sciences, School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington Campus, Loughborough, LE12 5RD, UK.
Yi-Tian FuHunan Provincial Key Laboratory of Protein Engineering in Animal Vaccines, College of Veterinary Medicine, Hunan Agricultural University, Changsha, 410128, Hunan, People's Republic of China.
Hiromu SugiyamaDepartment of Parasitology, National Institute of Infectious Diseases, Tokyo, 162-8640, Japan.
Katsuhiko AndoDepartment of Medical Zoology, Mie University School of Medicine, Mie, 514-8507, Japan.
Woon-Mok SohnDepartment of Parasitology and Tropical Medicine, Institute of Health Sciences, Gyeongsang National University College of Medicine, Jinju, 52727, Korea.
Xing-Quan ZhuCollege of Veterinary Medicine, Shanxi Agricultural University, Taigu, Shanxi, 030801, People's Republic of China. xingquanzhu1@hotmail.com.
Chaoqun YaoDepartment of Biomedical Sciences and One Health Center for Zoonoses and Tropical Veterinary Medicine, Ross University School of Veterinary Medicine, P.O. Box 334, Basseterre, St Kitts and Nevis. chyao@rossvet.edu.kn.

Funding

International Science and Technology Cooperation Programme 2013DFA31840the Training Program for Excellent Young Innovators of Changsha KQ 1905013
6 · The paper itself

Abstract

backgroundHuman gnathostomiasis is a food-borne zoonosis. Its etiological agents are the third-stage larvae of Gnathostoma spp. Human gnathostomiasis is often reported in developing countries, but it is also an emerging disease in developed countries in non-endemic areas. The recent surge in cases of human gnathostomiasis is mainly due to the increasing consumption of raw freshwater fish, amphibians, and reptiles.

methodsThis article reviews the literature on Gnathostoma spp. and the disease that these parasites cause in humans. We review the literature on the life cycle and pathogenesis of these parasites, the clinical features, epidemiology, diagnosis, treatment, control, and new molecular findings on human gnathostomiasis, and social-ecological factors related to the transmission of this disease.

conclusionsThe information presented provides an impetus for studying the parasite biology and host immunity. It is urgently needed to develop a quick and sensitive diagnosis and to develop an effective regimen for the management and control of human gnathostomiasis.

Indexed as

Food ParasitologyAnimalsFishesFoodborne DiseasesFresh WaterGnathostomaGnathostomiasisHumansImmunityLarvaLife Cycle StagesSocioeconomic FactorsZoonosesFood-borne zoonosisGnathostoma spp.Gnathostomiasis

Identifiers

PMID33298141
PMCPMC7724840

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.