Evidence map›Paper›PMID 33298010›Full record

ArticleBMC pregnancy and childbirth2020

The effect of a pharmacist consultation on pregnant women's quality of life with a special focus on nausea and vomiting: an intervention study.

Maria Bich-Thuy Truong, Elin Ngo, Hilde Ariansen, Ross T Tsuyuki, Hedvig Nordeng

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04182750 (Promoting Safe Medication Use in Pregnancy in the Era of Real-World Data - The SafeStart Study), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04182750 nacompletednot on this map

Promoting Safe Medication Use in Pregnancy in the Era of Real-World Data - The SafeStart Study

TypeinterventionalSponsorHedvig Marie Egeland NordengRan2018 to 2023Enrolled369ConditionsPregnancy Early, Emesis, Medication AdherenceArmsPharmacist consultation
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Maria Bich-Thuy TruongPharmacoepidemiology and Drug Safety Research Group, Department of Pharmacy, University of Oslo, Oslo, Norway. b.t.h.truong@farmasi.uio.no.ORCID http://orcid.org/0000-0001-9012-7010
Elin NgoPharmacoepidemiology and Drug Safety Research Group, Department of Pharmacy, University of Oslo, Oslo, Norway.ORCID https://orcid.org/0000-0001-9988-9257
Hilde AriansenThe Norwegian Pharmacy Association, Oslo, Norway.
Ross T TsuyukiDepartment of Pharmacology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada.ORCID https://orcid.org/0000-0002-3724-598X
Hedvig NordengPharmacoepidemiology and Drug Safety Research Group, Department of Pharmacy, University of Oslo, Oslo, Norway.ORCID https://orcid.org/0000-0001-6361-2918
University of Oslo · NONorwegian Institute of Public Health · NONorwegian Pharmacy Association · NOUniversity of Alberta · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMaternal wellbeing and quality of life (QOL) are increasingly being recognized as important for healthy pregnancies. The aim of this study was to investigate the impact of a pharmacist consultation on pregnant women's QOL focusing on nausea and vomiting in pregnancy (NVP), and patient satisfaction.

methodsFor this intervention study in 14 community pharmacies, women in early pregnancy were recruited and assigned to a pharmacist consultation (intervention) or standard care (control). The consultation aimed to address each woman's concerns regarding medications and pregnancy-related ailments. Data were collected through online questionnaires at baseline (Q1) and during the second trimester (Q2). The intervention group completed an additional satisfaction questionnaire after the consultation was completed. The primary outcome was the impact of the intervention on the Quality of Life Scale (QOLS) scores between the first and second trimesters. The impact of the intervention was assessed by linear regression, and secondary analyses were performed to assess effect modification by NVP.

resultsOf the 340 women enrolled in the study, we analyzed data for 245. Half (170/340) of the original participants were allocated to the intervention group, of whom 131 received the pharmacist consultation. Most women (75%, 78/96) reported that the consultation was useful to a large/very large extent. The consultation had no overall impact on QOLS scores between the first and the second trimesters compared with standard care (adjusted β: 0.7, 95% CI: -2.1, 3.4). The impact of the intervention on QOLS was greater amongst women with moderate/severe NVP (adjusted β: 3.6, 95% CI: -0.6, 7.7) compared to those with no/mild NVP (adjusted β: -1.4, 95% CI: -5.1, 2.2) (interaction term study group*NVP severity, p = 0.048).

conclusionsThe pregnant women highly appreciated the pharmacist consultation, but the intervention did not affect their QOL scores compared with standard care. Future studies should further explore the effect of a pharmacist consultation specifically for NVP and on other outcomes such as use of health care services and medication use in pregnancy.

trial registrationRetrospectively registered in ClinicalTrials.gov (identifier: NCT04182750 , registration date: December 2, 2019).

Indexed as

Patient SatisfactionPharmacistsQuality of LifeAdultCase-Control StudiesFemaleHumansNauseaNorwayPregnancyPregnancy ComplicationsPregnancy Trimester, FirstReferral and ConsultationSeverity of Illness IndexSurveys and QuestionnairesVomitingCommunity pharmacyMedicationsNausea and vomiting in pregnancyPharmacist interventionPregnancyQuality of life

Identifiers

PMID33298010
PMCPMC7727235
OpenAlexW3113179525

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.