Evidence map›Paper›PMID 33297989›Full record

Observational studyBMC nephrology2020

Left-ventricular diastolic dysfunction in Korean children with chronic kidney disease: data from the KNOW-Ped CKD study.

Jeong Yeon Kim, Yeonhee Lee, Hee Gyung Kang, Il-Soo Ha, Hae Il Cheong, Hyun Jin Choi, Kyoung Hee Han, Seong Heon Kim, Min Hyun Cho, Jae Il Shin and 3 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 1 country.

Jeong Yeon KimDepartment of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, South Korea.
Yeonhee LeeDepartment of Pediatrics, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Hee Gyung KangDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, South Korea.
Il-Soo HaDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, South Korea.
Hae Il CheongDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, South Korea.
Hyun Jin ChoiNational Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Chungcheongbuk-do, South Korea.
Kyoung Hee HanDepartment of Pediatrics, Jeju University Hospital, Jeju, South Korea.
Seong Heon KimDepartment of Pediatrics, Pusan National University Children's Hospital, Yangsan, South Korea.
Min Hyun ChoDepartment of Pediatrics, Kyungpook National University School of Medicine, Daegu, South Korea.
Jae Il ShinDepartment of Pediatrics, Yonsei University College of Medicine, Severance Children's Hospital, Seoul, South Korea.
Joo Hoon LeeDepartment of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, South Korea.
Young Seo ParkDepartment of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, South Korea.
Heeyeon ChoDepartment of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, South Korea. choheeyeon@gmail.com.ORCID 0000-0003-3137-6054
Seoul National University Children's Hospital · KRSamsung Medical Center · KRUlsan College · KRJeju National University Hospital · KRKyungpook National University · KRMinistry of Food and Drug Safety · KRPusan National University Yangsan Hospital · KRThe Catholic University of Korea Seoul St. Mary's Hospital · KRYonsei University · KR

Funding

Korea Centers for Disease Control and Prevention 2016E3300201
6 · The paper itself

Abstract

backgroundCardiovascular disease (CVD) is the most common cause of mortality in pediatric chronic kidney disease (CKD) patients. Left ventricular (LV) hypertrophy (LVH) is associated with LV diastolic dysfunction (LVDD) development and is used as an early marker of CVD in pediatric CKD. This study aimed to assess the prevalence and risk factors of LVDD and the association between LVH and LVDD in Korean pediatric CKD patients.

methodsData were collected using the baseline data of the Korean cohort study for outcome in patients with pediatric chronic kidney disease, a nationwide, 10-year, prospective, observational cohort study of pediatric CKD. A total of 244 patients were included in the final analysis. Two-dimensional echocardiography and tissue Doppler images were used to evaluate LVH and LVDD. LVH was defined as an LV mass index (LVMI) ≥38 g/m

resultsIn this study, the male-to-female ratio was 2.2 (168:76) and median age was 11.2 years. The average estimated glomerular filtration rate was 57.4 ml/min/1.73 m

conclusionThis study shows that LVH patients have a greater risk of LVDD and that anemia is the only modifiable risk factor for LVDD in Korean pediatric CKD patients.

Indexed as

AdolescentAnemiaAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsChildChild, PreschoolCohort StudiesDiastoleFemaleGlomerular Filtration RateHumansHypertrophy, Left VentricularInfantLogistic ModelsMaleMultivariate AnalysisAngiotensin-Converting Enzyme InhibitorsAngiotensin Receptor AntagonistsChildrenChronic kidney diseaseLeft ventricular diastolic dysfunction

Identifiers

PMID33297989
PMCPMC7724800
OpenAlexW3111684337

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.