SynthesisBMC cardiovascular disorders2020
Physical functional performance and prognosis in patients with heart failure: a systematic review and meta-analysis.
Synthesis in BMC cardiovascular disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
82 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Effectiveness of postoperative rehabilitation after discharge in survivors of esophageal or gastroesophageal junction cancers: a systematic review.Esophagus : official journal of the Japan Esophageal Society · 2026Pooled it
- Prevalence and Levels of Thyroid Autoantibodies in Polycystic Ovary Syndrome-Impact of TSH- and BMI-Matched Comparisons: A Systematic Review and Meta-Analysis.International journal of molecular sciences · 2025Pooled it
- Are sarcopenia and its individual components linked to all-cause mortality in heart failure? A systematic review and meta-analysis.Clinical research in cardiology : official journal of the German Cardiac Society · 2025Pooled it
- Cardiorespiratory fitness is a strong and consistent predictor of morbidity and mortality among adults: an overview of meta-analyses representing over 20.9 million observations from 199 unique cohort studies.British journal of sports medicine · 2024Pooled it
- Measurement properties of instruments to measure the fatigue domain of vitality capacity in community-dwelling older people: an umbrella review of systematic reviews and meta-analysis.Age and ageing · 2023Pooled it
- Physical function and all-cause mortality in patients with chronic kidney disease and end-stage renal disease: a systematic review and meta-analysis.International urology and nephrology · 2023Pooled it
- Physical function predicts mortality in patients with cancer: a systematic review and meta-analysis of observational studies.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Pooled it
- Prognostic value of baseline and longitudinal changes in exercise capacity and quality of life in the HF-Wii Swedish population.Open heart · 2026Trial
- Bridging the post-hospitalization gap: a feasibility study of home-based rehabilitation in decompensated heart failure.ESC heart failure · 2026Trial
- The Impact of Home Cardiac Rehabilitation on Quality of Life and Psychological Well-Being in Patients with Coronary Heart Disease: A Randomized Controlled Study.Medical science monitor : international medical journal of experimental and clinical research · 2024Trial
- Biomarkers and the quadriceps femoris muscle architecture assessed by ultrasound in older adults with heart failure with preserved ejection fraction: a cross-sectional study.Aging clinical and experimental research · 2022Trial
- The effects of early rehabilitation on functional exercise tolerance in decompensated heart failure patients: Results of a multicenter randomized controlled trial (ERIC-HF study).Clinical rehabilitation · 2022Trial
- Association between comorbidity burden and subclinical cardiac dysfunction in cancer patients prior to chemotherapy.Hong Kong physiotherapy journal : official publication of the Hong Kong Physiotherapy Association Limited = Wu li chih liao · 2026Article
- A cardiovascular-motor axis framework for perfusion-mediated motor impairment.International journal of cardiology. Heart & vasculature · 2026Review
- Exercise testing for evaluating right ventricular (RV) function in pulmonary hypertension - A review.Lung India : official organ of Indian Chest Society · 2026Article
- Health-Related Quality of Life and Associated Factors in Patients with Heart Failure Across Three Ejection Fraction Categories: A Two-Center Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
- Novel Gait Speed Cut-Off Values Associated With Prognosis in Older Patients With Heart Failure.Geriatrics & gerontology international · 2026Article
- Improving Physical Performance During Hospitalization Has an Impact on Reducing the Risk of Clinical Events in Frail Older Patients With Acutely Decompensated Heart Failure.Circulation reports · 2026Article
- Functional Thresholds Derived from Dynamometry and 6-Minute Walk Test with Morphofunctional Assessment to Guide Individualized Exercise Prescription in Cardiac Rehabilitation.Journal of clinical medicine · 2026Article
- Association Between Locomotive Syndrome and N-Terminal Pro B-Type Natriuretic Peptide Concentration in a Health Screening Cohort: A Retrospective Cross-Sectional Study.Circulation reports · 2026Article
22 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with Heart Failure (HF) show impaired functional capacities which have been related to their prognosis. Moreover, physical functional performance in functional tests has also been related to the prognosis in patients with HF. Thus, it would be useful to investigate how physical functional performance in functional tests could determine the prognosis in patients with HF, because HF is the leading cause of hospital admissions for people older than 65 years old. This systematic review and meta-analysis aims to summarise and synthesise the evidence published about the relationship between physical functional performance and prognosis in patients with HF, as well as assess the risk of bias of included studies and the level of evidence per outcome.
methodsMajor electronic databases, such as PubMed, AMED, CINAHL, EMBASE, PEDro, Web of Science, were searched from inception to March 2020 for observational longitudinal cohort studies (prospective or retrospective) examining the relationship between physical functional performance and prognosis in patients with HF.
results44 observational longitudinal cohort studies with a total of 22,598 patients with HF were included. 26 included studies reported a low risk of bias, and 17 included studies showed a moderate risk of bias. Patients with poor physical functional performance in the Six Minute Walking Test (6MWT), in the Short Physical Performance Battery (SPPB) and in the Gait Speed Test showed worse prognosis in terms of larger risk of hospitalisation or mortality than patients with good physical functional performance. However, there was a lack of homogeneity regarding which cut-off points should be used to stratify patients with poor physical functional performance from patients with good physical functional performance.
conclusionThe review includes a large number of studies which show a strong relationship between physical functional performance and prognosis in patients with HF. Most of the included studies reported a low risk of bias, and GRADE criteria showed a low and a moderate level of evidence per outcome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.