Evidence map›Paper›PMID 33297946›Full record

ArticleBMC genomics2020

RBPsuite: RNA-protein binding sites prediction suite based on deep learning.

Xiaoyong Pan, Yi Fang, Xianfeng Li, Yang Yang, Hong-Bin Shen

Open access · goldAbstract read
In one paragraph

Article in BMC genomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 115 citations in OpenAlex.

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  14. mAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
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10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Xiaoyong PanInstitute of Image Processing and Pattern Recognition, Shanghai Jiao Tong University, and Key Laboratory of System Control and Information Processing, Ministry of Education of China, Shanghai, 200240, China. 2008xypan@sjtu.edu.cn.ORCID http://orcid.org/0000-0001-5010-464X
Yi FangInstitute of Image Processing and Pattern Recognition, Shanghai Jiao Tong University, and Key Laboratory of System Control and Information Processing, Ministry of Education of China, Shanghai, 200240, China.
Xianfeng LiKey laboratory of Carcinogenesis and Translational Research, Peking University Cancer Hospital, Beijing, 100142, China.
Yang YangDepartment of Computer Science and Engineering, Shanghai Jiao Tong University, Center for Brain-Like Computing and Machine Intelligence, Shanghai, 200240, China.
Hong-Bin ShenInstitute of Image Processing and Pattern Recognition, Shanghai Jiao Tong University, and Key Laboratory of System Control and Information Processing, Ministry of Education of China, Shanghai, 200240, China. hbshen@sjtu.edu.cn.
Shanghai Jiao Tong University · CNPeking University · CN

Funding

National Natural Science Foundation of China 61903248
6 · The paper itself

Abstract

backgroundRNA-binding proteins (RBPs) play crucial roles in various biological processes. Deep learning-based methods have been demonstrated powerful on predicting RBP sites on RNAs. However, the training of deep learning models is very time-intensive and computationally intensive.

resultsHere we present a deep learning-based RBPsuite, an easy-to-use webserver for predicting RBP binding sites on linear and circular RNAs. For linear RNAs, RBPsuite predicts the RBP binding scores with them using our updated iDeepS. For circular RNAs (circRNAs), RBPsuite predicts the RBP binding scores with them using our developed CRIP. RBPsuite first breaks the input RNA sequence into segments of 101 nucleotides and scores the interaction between the segments and the RBPs. RBPsuite further detects the verified motifs on the binding segments gives the binding scores distribution along the full-length sequence.

conclusionsRBPsuite is an easy-to-use online webserver for predicting RBP binding sites and freely available at http://www.csbio.sjtu.edu.cn/bioinf/RBPsuite/ .

Indexed as

Deep LearningRNABinding SitesProtein BindingRNA-Binding ProteinsRNARNA-Binding ProteinsCircular RNAsDeep learningLinear RNAsRNA-binding proteins

Identifiers

PMID33297946
PMCPMC7724624
OpenAlexW3112745729

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.