Evidence map›Paper›PMID 33297753›Full record

ArticleArteriosclerosis, thrombosis, and vascular biology2021

Pronethalol Reduces Sox2 (SRY [Sex-Determining Region Y]-Box 2) to Ameliorate Vascular Calcification.

Daoqin Zhang, Xiaojing Qiao, Jiayi Yao, Li Zhang, Xiuju Wu, Jocelyn Ma, Xinjiang Cai, Kristina I Bostrom, Yucheng Yao

Open access · bronzeAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Arteriosclerosis, thrombosis, and vascular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. GSK3β Inhibition Reduced Vascular Calcification inInternational journal of molecular sciences · 2023
    Article
  5. Article
  6. Role of endothelial cells in vascular calcification.Frontiers in cardiovascular medicine · 2022
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Daoqin ZhangDivision of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA (D.Z., X.Q., J.Y., L.Z., X.W., J.M., X.C., K.I.B., Y.Y.).
Xiaojing QiaoDivision of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA (D.Z., X.Q., J.Y., L.Z., X.W., J.M., X.C., K.I.B., Y.Y.).
Jiayi YaoDivision of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA (D.Z., X.Q., J.Y., L.Z., X.W., J.M., X.C., K.I.B., Y.Y.).
Li ZhangDivision of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA (D.Z., X.Q., J.Y., L.Z., X.W., J.M., X.C., K.I.B., Y.Y.).
Xiuju WuDivision of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA (D.Z., X.Q., J.Y., L.Z., X.W., J.M., X.C., K.I.B., Y.Y.).
Jocelyn MaDivision of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA (D.Z., X.Q., J.Y., L.Z., X.W., J.M., X.C., K.I.B., Y.Y.).
Xinjiang CaiDivision of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA (D.Z., X.Q., J.Y., L.Z., X.W., J.M., X.C., K.I.B., Y.Y.).
Kristina I BostromDivision of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA (D.Z., X.Q., J.Y., L.Z., X.W., J.M., X.C., K.I.B., Y.Y.).
Yucheng YaoDivision of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA (D.Z., X.Q., J.Y., L.Z., X.W., J.M., X.C., K.I.B., Y.Y.).
World Wide Web Consortium · USUniversity of California, Los Angeles · US

Funding

ULTRASTRUCTURE OF THE INTIMA IN EARLY LESION FORMATIONP01HL030568 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI FOGELMAN, ALAN M · 1985 to 2019
$55.2M
Molecular Mechanisms of MGP; Role in AVMsR01HL081397 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BOSTROM, KRISTINA I · 2006 to 2025
$7.7M
BMP and Notch Crosstalk in Cerebral Arteriovenous MalformationsR01NS079353 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Yucheng Yao · 2012 to 2026
$5.3M
Switch of Osteogenesis in Vascular CalcificationR01HL139675 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Yucheng Yao · 2018 to 2026
$3.6M
NHLBI NIH HHS P01 HL030568NHLBI NIH HHS R01 HL081397NHLBI NIH HHS R01 HL139675NINDS NIH HHS R01 NS079353
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adrenergic beta-AntagonistsAnimalsAortic DiseasesAtherosclerosisCalcium-Binding ProteinsDiabetes MellitusDisease Models, AnimalDown-RegulationEndothelial CellsEthanolaminesExtracellular Matrix ProteinsMatrix Gla ProteinMiceMice, KnockoutMice, Knockout, ApoEOsteopontinAdrenergic beta-AntagonistsCalcium-Binding ProteinsEthanolaminesExtracellular Matrix ProteinsMatrix Gla ProteinOsteopontinpronethalolSnai2 protein, mouseSnail Family Transcription FactorsSox2 protein, mouseSOXB1 Transcription FactorsSpp1 protein, mouseaortadiet, high-fatendothelial cellmicepronethalol

Identifiers

PMID33297753
PMCPMC8105260
OpenAlexW3112157679

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.