Evidence map›Paper›PMID 33297678›Full record

ArticleAnalytical chemistry2021

Measurement of Neuropeptide Y Using Aptamer-Modified Microelectrodes by Electrochemical Impedance Spectroscopy.

Luis López, Nerika Hernández, Joshua Reyes Morales, John Cruz, Krystal Flores, John González-Amoretti, Vitmary Rivera, Lisandro Cunci

Open access · greenAbstract read
In one paragraph

Article in Analytical chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Neuropeptidergic systems in psychiatric disorders.Frontiers in endocrinology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Luis LópezDepartment of Chemistry, Universidad Ana G. Méndez, Carr. 189, Km 3.3, Gurabo, Puerto Rico 00778, United States.
Nerika HernándezDepartment of Chemistry, Universidad Ana G. Méndez, Carr. 189, Km 3.3, Gurabo, Puerto Rico 00778, United States.
Joshua Reyes MoralesDepartment of Chemistry, Universidad Ana G. Méndez, Carr. 189, Km 3.3, Gurabo, Puerto Rico 00778, United States.
John CruzDepartment of Chemistry, Universidad Ana G. Méndez, Carr. 189, Km 3.3, Gurabo, Puerto Rico 00778, United States.
Krystal FloresDepartment of Chemistry, Universidad Ana G. Méndez, Carr. 189, Km 3.3, Gurabo, Puerto Rico 00778, United States.
John González-AmorettiDepartment of Chemistry, Universidad Ana G. Méndez, Carr. 189, Km 3.3, Gurabo, Puerto Rico 00778, United States.
Vitmary RiveraDepartment of Chemistry, Universidad Ana G. Méndez, Carr. 189, Km 3.3, Gurabo, Puerto Rico 00778, United States.
Lisandro CunciDepartment of Chemistry, Universidad Ana G. Méndez, Carr. 189, Km 3.3, Gurabo, Puerto Rico 00778, United States.ORCID 0000-0002-7315-177X
Ana G. Mendez University System · PR

Funding

SCIENCE AND TECHNOLOGY COMPETENCY & EDUCATION CORE (STCE)P20GM103475 · NIGMS · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI Jose R. Rodriguez-Medina · 2012 to 2026
$52.9M
NASA NNX15AI11HNIGMS NIH HHS P20 GM103475
6 · The paper itself

Abstract

Aptamer-modified microelectrodes for Neuropeptide Y measurement by electrochemical impedance spectroscopy was described here. The advantages of using carbon fiber or platinum microelectrodes are because they are promising materials with high electrical conductivity, chemical stability, and high surface area that can be easily modified on their surface. The immobilization and biofouling were studied and compared using EIS. Moreover, the adsorption of NPY to the aptamer-modified microelectrodes was also demonstrated by EIS. Changes of -ω*

Indexed as

Biosensing TechniquesDielectric SpectroscopyAptamers, NucleotideCarbon FiberMicroelectrodesNeuropeptide YPlatinumSurface PropertiesAptamers, NucleotideCarbon FiberNeuropeptide YPlatinum

Identifiers

PMID33297678
PMCPMC7856015
OpenAlexW3113374850

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.