Evidence map›Paper›PMID 33297474›Full record

ArticleAnimals : an open access journal from MDPI2020

Assessment of the Cardiac Functions Using Full Conventional Echocardiography with Tissue Doppler Imaging before and after Xylazine Sedation in Male Shiba Goats.

Ahmed S Mandour, Haney Samir, Tomohiko Yoshida, Katsuhiro Matsuura, Hend A Abdelmageed, Mohamed Elbadawy, Salim Al-Rejaie, Hussein M El-Husseiny, Ahmed Elfadadny, Danfu Ma and 3 more

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 3 countries.

Ahmed S MandourDepartment of Animal Medicine (Internal Medicine), Faculty of Veterinary Medicine, Suez Canal University, Ismailia 41522, Egypt.ORCID 0000-0001-6256-4539
Haney SamirDepartment of Theriogenology, Faculty of Veterinary Medicine, Cairo University, Giza 12211, Egypt.ORCID 0000-0002-0594-3986
Tomohiko YoshidaLaboratory of Veterinary Surgery, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan.
Katsuhiro MatsuuraLaboratory of Veterinary Surgery, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan.ORCID 0000-0002-6047-2865
Hend A AbdelmageedLaboratory of Veterinary Microbiology, Animal Health Research Institute, Ismailia lab, First District, Ismailia 41522, Egypt.
Mohamed ElbadawyDepartment of Pharmacology, Faculty of Veterinary Medicine, Benha University, Moshtohor, Toukh, Elqaliobiya 13736, Egypt.ORCID 0000-0001-9368-1535
Salim Al-RejaieDepartment of Pharmacology & Toxicology, College of Pharmacy, King Saud University, Riyadh 11564, Saudi Arabia.
Hussein M El-HusseinyLaboratory of Veterinary Surgery, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan.ORCID 0000-0003-1143-4018
Ahmed ElfadadnyDepartment of Animal Medicine, Faculty of Veterinary Medicine, Damanhur University, Damanhur, El-Beheira 22511, Egypt.ORCID 0000-0002-0361-1507
Danfu MaLaboratory of Veterinary Surgery, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan.ORCID 0000-0002-6557-7703
Ken TakahashiDepartment of Pediatrics and Adolescent Medicine, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan.
Gen WatanabeLaboratory of Veterinary Physiology, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan.
Ryou TanakaLaboratory of Veterinary Surgery, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan.ORCID 0000-0001-9948-6490
Tokyo University of Agriculture and Technology · JPBenha University · EGCairo University · EGDamanhour University · EGJuntendo University · JPKing Saud University · SASuez Canal University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study aimed to provide a complete conventional echocardiographic protocol in adult male Shiba goats by using two-dimensional, M-mode, Pulsed Wave Doppler, and tissue Doppler imaging (TDI) echocardiography, and to study concomitantly xylazine-induced alteration of cardiac functions in a highly sensitive species. For this purpose, 12 male Shiba goats were included and complete conventional echocardiography from the standard right and left parasternal views was carried to report the echocardiographic data in male Shiba goats, and also before and after xylazine (Pre-Xyl and Post-Xyl) administration (0.05 mg/IM/kg). Results revealed that the full echocardiographic protocol was feasible in all goats through different cardiac windows and good Doppler alignment was achieved with non-significant variability for assessment of the left ventricular dimensions, trans-pulmonary, trans-aortic, and trans-mitral blood flow. The TDI, which was not reported previously in goats, was successfully assessed from the standard left apical view and showed distinct systolic and diastolic patterns. Xylazine administration was found to significantly reduce heart rate, fractional shortening, and cardiac output as well as the Doppler hemodynamic parameters of the pulmonary artery, aortic and mitral inflows (

Indexed as

Doppler echocardiographygoatshearttissue Doppler imagingxylazine

Identifiers

PMID33297474
PMCPMC7762359
OpenAlexW3110983940

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.