Evidence map›Paper›PMID 33297445›Full record

ArticleInternational journal of environmental research and public health2020

Dengue Seroprevalence and Seroconversion in Urban and Rural Populations in Northeastern Thailand and Southern Laos.

Dyna Doum, Hans J Overgaard, Mayfong Mayxay, Sutas Suttiprapa, Prasert Saichua, Tipaya Ekalaksananan, Panwad Tongchai, Md Siddikur Rahman, Ubydul Haque, Sysavanh Phommachanh and 4 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
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  6. Mapping landscape changes to address dengue fever risk in Laos and Thailand.Current research in parasitology & vector-borne diseases · 2026
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  16. Dengue Seroprevalence and Factors Associated with Dengue Seropositivity in Petaling District, Malaysia.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 8 countries.

Dyna DoumTropical Medicine Graduate Program, Academic Affairs, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0002-2664-3819
Hans J OvergaardDepartment of Microbiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Mayfong MayxayInstitute of Research and Education Development (IRED), University of Health Sciences, Ministry of Health, P.O. Box 7444, Vientiane 43130, Laos.
Sutas SuttiprapaTropical Medicine Graduate Program, Academic Affairs, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Prasert SaichuaTropical Medicine Graduate Program, Academic Affairs, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Tipaya EkalaksanananDepartment of Microbiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Panwad TongchaiDepartment of Microbiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Md Siddikur RahmanDepartment of Microbiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.ORCID 0000-0001-8925-6544
Ubydul HaqueDepartment of Biostatistics and Epidemiology, University of North Texas Health Science Center, Fort Worth, TX 76177, USA.ORCID 0000-0002-7413-1017
Sysavanh PhommachanhInstitute of Research and Education Development (IRED), University of Health Sciences, Ministry of Health, P.O. Box 7444, Vientiane 43130, Laos.
Tiengkham PongvongsaSavannakhet Provincial Health Department, Savannakhet 13000, Laos.
Joacim RocklövDepartment of Public Health and Clinical Medicine, Umeå University, 90187 Umeå, Sweden.ORCID 0000-0003-4030-0449
Richard PaulUnité de la Génétique Fonctionnelle des Maladies Infectieuses, Institut Pasteur, CNRS UMR 2000, 75015 Paris, France.ORCID 0000-0002-0665-5089
Chamsai PientongDepartment of Microbiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.
Khon Kaen University · THBegum Rokeya University · BDCentre National de la Recherche Scientifique · FRMahosot Hospital · LAMinistry of Health · LAUmeå University · SEUniversity of North Texas · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dengue is the most rapidly spreading mosquito-borne viral disease in the world. The detection of clinical cases enables us to measure the incidence of dengue infection, whereas serological surveys give insights into the prevalence of infection. This study aimed to determine dengue seroprevalence and seroconversion rates in northeastern Thailand and southern Laos and to assess any association of mosquito control methods and socioeconomic factors with dengue virus (DENV) infection. Cross-sectional seroprevalence surveys were performed in May and November 2019 on the same individuals. Blood samples were collected from one adult and one child, when possible, in each of 720 randomly selected households from two urban and two rural sites in both northeastern Thailand and southern Laos. IgG antibodies against DENV were detected in serum using a commercial enzyme-linked immunosorbent assay (ELISA) kit. Overall, 1071 individuals participated in the study. The seroprevalence rate was high (91.5%) across all 8 study sites. Only age and province were associated with seroprevalence rates. There were 33 seroconversions during the period from May to November, of which seven reported fever. More than half of the seroconversions occurred in the rural areas and in Laos. Dengue seroconversion was significantly associated with young age (<15 years old), female gender, province, and duration of living in the current residence. No socioeconomic factors or mosquito control methods were found to be associated with seroprevalence or seroconversion. Notably, however, the province with most seroconversions had lower diurnal temperature ranges than elsewhere. In conclusion, our study has highlighted the homogeneity of dengue exposure across a wide range of settings and most notably those from rural and urban areas. Dengue can no longer be considered to be solely an urban disease nor necessarily one linked to poverty.

Indexed as

DengueDengue VirusAdolescentAdultAnimalsAntibodies, ViralChildCross-Sectional StudiesEnzyme-Linked Immunosorbent AssayFemaleHumansLaosMaleRural PopulationSeroconversionSeroepidemiologic StudiesAntibodies, ViraldengueDENVseroconversionseroprevalencesocioeconomic factors

Identifiers

PMID33297445
PMCPMC7731008
OpenAlexW3112034967

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.