Evidence map›Paper›PMID 33297081›Full record

ArticleChemosphere2021

Dominant entropic binding of perfluoroalkyl substances (PFASs) to albumin protein revealed by

Michael Fedorenko, Jessica Alesio, Anatoliy Fedorenko, Angela Slitt, Geoffrey D Bothun

Open access · greenAbstract read
In one paragraph

Article in Chemosphere, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Michael FedorenkoDepartment of Chemical Engineering, University of Rhode Island, 2 East Alumni Ave, Kingston, RI, 02881, USA.
Jessica AlesioDepartment of Chemical Engineering, University of Rhode Island, 2 East Alumni Ave, Kingston, RI, 02881, USA.
Anatoliy FedorenkoDepartment of Chemical Engineering, University of Rhode Island, 2 East Alumni Ave, Kingston, RI, 02881, USA.
Angela SlittDepartment of Biomedical & Pharmaceutical Sciences, University of Rhode Island, 7 Greenhouse Rd, Kingston, RI, 02881, USA.
Geoffrey D BothunDepartment of Chemical Engineering, University of Rhode Island, 2 East Alumni Ave, Kingston, RI, 02881, USA. Electronic address: gbothun@uri.edu.
University of Rhode Island · US

Funding

Sources, Transport, Exposure & Effects of PFAS (STEEP) Center - RENEWALP42ES027706 · NIEHS · UNIVERSITY OF RHODE ISLAND · PI Harrison Dekker · 2017 to 2026
$18.9M
NIEHS NIH HHS P42 ES027706
6 · The paper itself

Abstract

Mechanistic insight into protein binding by poly- and perfluoroalkyl substances (PFASs) is critical to understanding how PFASs distribute and accumulate within the body and to developing predictive models within and across classes of PFASs. Fluorine nuclear magnetic resonance spectroscopy (

Indexed as

Alkanesulfonic AcidsEnvironmental PollutantsFluorocarbonsAlbuminsEntropyMagnetic Resonance SpectroscopyAlbuminsAlkanesulfonic AcidsEnvironmental PollutantsFluorocarbonsAlbuminNMRPFASProtein binding

Identifiers

PMID33297081
PMCPMC8479757
OpenAlexW3081783700

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.