ArticleImmunity2020
Low-Avidity CD4
Open access · bronzeAbstract read
In one paragraph
Article in Immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 215 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
215citing papers in PubMed, 1 pooled it
6.7field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
215 citing papers in PubMed, 1 synthesis or guideline pooled it, 341 citations in OpenAlex.
- Resolving SARS-CoV-2 CD4Cell reports. Medicine · 2022Pooled it
- CD4+ T cells from COVID-19 mRNA vaccine recipients recognize a conserved epitope present in diverse coronaviruses.The Journal of clinical investigation · 2022Trial
- Single-cell immune profiling reveals distinct immune response in asymptomatic COVID-19 patients.Signal transduction and targeted therapy · 2021Trial
- T cell immunomonitoring: a comparative analysis of traditional and novel methods to quantify and characterize human antigen-specific T cells.Nature protocols · 2026Review
- A decade of endemic human coronaviruses: epidemiological patterns and clinical significance in an adult cohort at a tertiary care hospital in Germany.BMC infectious diseases · 2026Article
- Article
- The challenge and promise of studying human antigen-specific T cells.Nature reviews. Immunology · 2026Review
- Article
- Serial vaccination expands and refines human CD4bioRxiv : the preprint server for biology · 2026Article
- Cytotoxic CD4Signal transduction and targeted therapy · 2026Review
- A Lung-Immune Dual-Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- A modular three in one mucosal vaccine against three antigenic clusters of ACE2 using sarbecoviruses.NPJ vaccines · 2026Article
- A multiparameter whole blood platform for assessment of anti-CMV immunity in allogeneic stem cell transplantation recipients.Frontiers in immunology · 2026Article
- A novel chimeric coronavirus spike vaccine combining SARS-CoV-2 RBD and scaffold domains from HKU-1 elicits potent neutralising antibody responses.NPJ vaccines · 2025Article
- Article
- Delayed Cellular Immunity in SARS-CoV-2 Antibody-Non-Responders to COVID-19 Vaccination: Rethinking Post-Vaccine Immune Assessment.Vaccines · 2025Article
- Long-persisting SARS-CoV-2 spike-specific CD4Nature communications · 2025Article
- cytoKernel: robust kernel embeddings for assessing differential expression of single-cell data.Bioinformatics (Oxford, England) · 2025Article
- Effect of prevaccination blood and T-cell phenotypes on antibody responses to a COVID-19 mRNA vaccine.International immunology · 2025Article
- Endemic coronavirus infection is associated with SARS-CoV-2 Fc receptor-binding antibodies.Journal of virology · 2025Article
155 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
27 authors at 5 institutions in 1 country.
Petra BacherInstitute of Immunology, Christian-Albrechts-University of Kiel & UKSH Schleswig-Holstein, Kiel, Germany; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany. Electronic address: p.bacher@ikmb.uni-kiel.de.
Elisa RosatiInstitute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany.
Daniela EsserInstitute of Clinical Chemistry, University Hospital Schleswig-Holstein, Kiel/ Lübeck, Germany.
Gabriela Rios MartiniInstitute of Immunology, Christian-Albrechts-University of Kiel & UKSH Schleswig-Holstein, Kiel, Germany; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany.
Carina SaggauInstitute of Immunology, Christian-Albrechts-University of Kiel & UKSH Schleswig-Holstein, Kiel, Germany.
Esther SchiminskyInstitute of Immunology, Christian-Albrechts-University of Kiel & UKSH Schleswig-Holstein, Kiel, Germany.
Justina DargvainieneInstitute of Clinical Chemistry, University Hospital Schleswig-Holstein, Kiel/ Lübeck, Germany.
Ina SchröderInstitute of Clinical Chemistry, University Hospital Schleswig-Holstein, Kiel/ Lübeck, Germany.
Imke WietersDepartment of Internal Medicine, Infectious Diseases, University Hospital Frankfurt & Goethe University Frankfurt, Frankfurt am Main, Germany.
Yascha KhodamoradiDepartment of Internal Medicine, Infectious Diseases, University Hospital Frankfurt & Goethe University Frankfurt, Frankfurt am Main, Germany.
Fabian EberhardtDepartment of Internal Medicine, Infectious Diseases, University Hospital Frankfurt & Goethe University Frankfurt, Frankfurt am Main, Germany.
Maria J G T VehreschildDepartment of Internal Medicine, Infectious Diseases, University Hospital Frankfurt & Goethe University Frankfurt, Frankfurt am Main, Germany.
Holger NebDepartment of Anesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt am Main, Germany.
Michael SonntagbauerDepartment of Anesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt am Main, Germany.
Claudio ConradDepartment of Internal Medicine, Hospital of Preetz, Preetz, Germany.
Florian TranInstitute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany; Department of Internal Medicine I, UKSH Kiel, Germany.
Philip RosenstielInstitute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany.
Robert MarkewitzInstitute of Clinical Chemistry, University Hospital Schleswig-Holstein, Kiel/ Lübeck, Germany.
Klaus-Peter WandingerInstitute of Clinical Chemistry, University Hospital Schleswig-Holstein, Kiel/ Lübeck, Germany.
Max AugustinUniversity of Cologne, Medical Faculty and University Hospital Cologne, Department I of Internal Medicine, Cologne, Germany; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany; University of Cologne, Medical Faculty and University Hospital Cologne, German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany.
Jan RybnikerUniversity of Cologne, Medical Faculty and University Hospital Cologne, Department I of Internal Medicine, Cologne, Germany; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany; University of Cologne, Medical Faculty and University Hospital Cologne, German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany.
Matthias KochanekUniversity of Cologne, Medical Faculty and University Hospital Cologne, Department I of Internal Medicine, Cologne, Germany.
Frank LeypoldtInstitute of Clinical Chemistry, University Hospital Schleswig-Holstein, Kiel/ Lübeck, Germany; Department of Neurology, University Hospital Schleswig-Holstein, Kiel, Germany.
Oliver A CornelyUniversity of Cologne, Medical Faculty and University Hospital Cologne, Department I of Internal Medicine, Cologne, Germany; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany; University of Cologne, Medical Faculty and University Hospital Cologne, German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany; Clinical Trials Centre Cologne, ZKS Köln, Cologne, Germany; University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany.
Philipp KoehlerUniversity of Cologne, Medical Faculty and University Hospital Cologne, Department I of Internal Medicine, Cologne, Germany; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany; University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany.
Andre FrankeInstitute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany.
Alexander ScheffoldInstitute of Immunology, Christian-Albrechts-University of Kiel & UKSH Schleswig-Holstein, Kiel, Germany.
Christian-Albrechts-Universität zu Kiel · DEGoethe University Frankfurt · DEUniversity Hospital Schleswig-Holstein · DEUniversity of Cologne · DEKlinik Preetz · DE
Funding
No grant is acknowledged in the PubMed record.
Abstract
CD4
Indexed as
Antigens, ViralCD4-Positive T-LymphocytesCells, CulturedCOVID-19Cross ReactionsDisease ProgressionEnvironmental ExposureHumansImmunologic MemoryLymphocyte ActivationProtein BindingReceptors, Antigen, T-CellRhinovirusSARS-CoV-2Severity of Illness IndexT-Cell Antigen Receptor SpecificityAntigens, ViralReceptors, Antigen, T-Cellantigen-reactive T cell enrichmentantigen-specific T cellsARTEcommon cold coronavirusCOVID-19human coronaviruspre-existing memorySARS-CoV-2T cell cross-reactivity
Identifiers
What OpenQuestion holds
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Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.