Evidence map›Paper›PMID 33296604›Full record

ArticleThe Journal of international medical research2020

Development and validation of a novel prognostic model for long-term overall survival in liposarcoma patients: a population-based study.

Shuai Cao, Jie Li, Kai Yang, Jun Zhang, Jiawei Xu, Chaoshuai Feng, Haopeng Li

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Article in The Journal of international medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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5citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Shuai CaoDepartment of Orthopedics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Jie LiDepartment of Orthopedics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Kai YangDepartment of Orthopedics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Jun ZhangSchool of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Jiawei XuDepartment of Orthopedics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Chaoshuai FengDepartment of Orthopedics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Haopeng LiDepartment of Orthopedics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo construct and validate a clinically accurate and histology-specific nomogram to predict overall survival (OS) among liposarcoma (LPS) patients.

methodsWe retrospectively screened eligible patients with LPS diagnosed between 2004 and 2015 from the Surveillance, Epidemiology, and End Results database. We screened independent predictors for the nomogram using univariate and multivariate analyses. We then evaluated the prognostic accuracy of the nomogram by receiver operating characteristic (ROC) curve analysis and Harrell's concordance index. The prognostic performances of the nomogram and the American Joint Committee on Cancer (AJCC) seventh edition staging system were compared using integrated discrimination improvement (IDI), net reclassification improvement (NRI), and decision curve analyses (DCA).

resultsA novel nomogram was developed using independent prognostic variables, which exhibited excellent predictive performances for 3- and 5-year OS according to ROC curves. The C-index proved that the proposed nomogram had better prognostic accuracy for LPS than the traditional AJCC system, while the NRI, IDI, and DCA of the nomogram indicated better clinical net benefit.

conclusionsThe proposed nomogram can predict 3- and 5-year OS of LPS patients with reliable accuracy and may thus help clinicians to develop appropriate clinical therapies and counseling strategies to prolong the life expectancy of these patients.

Indexed as

LiposarcomaNomogramsHumansPrognosisRetrospective StudiesSEER ProgramLiposarcomanomogramoverall survivalpredictionprognosisSEER database

Identifiers

PMID33296604
PMCPMC7731721

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