Evidence map›Paper›PMID 33296290›Full record

ArticleAmerican journal of respiratory and critical care medicine2021

Polyclonality, Shared Strains, and Convergent Evolution in Chronic Cystic Fibrosis

Dustin R Long, Daniel J Wolter, Michael Lee, Mimi Precit, Kathryn McLean, Elizabeth Holmes, Kelsi Penewit, Adam Waalkes, Lucas R Hoffman, Stephen J Salipante

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 48 citations in OpenAlex.

  1. Trial
  2. Intraspecific diversity ofMicrobiology spectrum · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Molecular epidemiology ofFrontiers in cellular and infection microbiology · 2026
    Article
  8. Microbial and host innate immune factors affecting the persistence ofFrontiers in cellular and infection microbiology · 2026
    Review
  9. Article
  10. Article
  11. Regulation of airway fumarate by host and pathogen promotesbioRxiv : the preprint server for biology · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Analysis of genetic requirements and nutrient availability forbioRxiv : the preprint server for biology · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Average Nucleotide Identity basedbioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Dustin R LongDivision of Critical Care Medicine, Department of Anesthesiology and Pain Medicine.ORCID 0000-0001-6365-953X
Daniel J WolterDepartment of Pediatrics.ORCID 0000-0003-4321-8520
Michael LeeDepartment of Pediatrics.
Mimi PrecitDepartment of Microbiology, and.ORCID 0000-0002-0720-8643
Kathryn McLeanDepartment of Laboratory Medicine and Pathology, School of Medicine, University of Washington, Seattle, Washington; and.ORCID 0000-0001-7986-0879
Elizabeth HolmesDepartment of Laboratory Medicine and Pathology, School of Medicine, University of Washington, Seattle, Washington; and.
Kelsi PenewitDepartment of Laboratory Medicine and Pathology, School of Medicine, University of Washington, Seattle, Washington; and.ORCID 0000-0003-1454-6381
Adam WaalkesDepartment of Laboratory Medicine and Pathology, School of Medicine, University of Washington, Seattle, Washington; and.ORCID 0000-0002-5202-1108
Lucas R HoffmanDepartment of Pediatrics.ORCID 0000-0001-8864-6751
Stephen J SalipanteDepartment of Laboratory Medicine and Pathology, School of Medicine, University of Washington, Seattle, Washington; and.ORCID 0000-0001-8355-6992
University of Washington · USSeattle Children's Hospital · USPain and Rehabilitation Medicine · US

Funding

Translational Research Center to Expedite Novel Therapies in Cystic FibrosisP30DK089507 · NIDDK · SEATTLE CHILDREN'S HOSPITAL · PI PRADEEP k SINGH · 2010 to 2026
$21.4M
Anesthesiology & Perioperative Medicine Training GrantT32GM086270 · NIGMS · UNIVERSITY OF WASHINGTON · PI Tonya M Palermo · 2009 to 2026
$4.3M
Patient-oriented microbiome and advanced culture approaches to identifying the microbial determinants of chronic pediatric diseaseK24HL141669 · NHLBI · UNIVERSITY OF WASHINGTON · PI Lucas R Hoffman · 2018 to 2026
$929k
NHLBI NIH HHS K24 HL141669NIDDK NIH HHS P30 DK089507NIGMS NIH HHS T32 GM086270
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdolescentAnti-Bacterial AgentsChildCohort StudiesCystic FibrosisFemaleHumansMaleMolecular EpidemiologyRespiratory Tract InfectionsStaphylococcal InfectionsStaphylococcus aureusAnti-Bacterial Agentscystic fibrosisinfectionmolecular epidemiologyStaphylococcus aureuswhole-genome sequencing

Identifiers

PMID33296290
PMCPMC8314914
OpenAlexW3111490566

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.