Evidence map›Paper›PMID 33296222›Full record

ArticleThe British journal of radiology2021

A CT-based radiomics nomogram for predicting prognosis of coronavirus disease 2019 (COVID-19) radiomics nomogram predicting COVID-19.

Hang Chen, Ming Zeng, Xinglan Wang, Liping Su, Yuwei Xia, Quan Yang, Dan Liu

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Article in The British journal of radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

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15citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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15 citing papers in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Hang ChenDepartment of Radiology, The Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Ming ZengDepartment of Respiratory and Critical Care Medicine, The Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Xinglan WangDepartment of Radiology, The Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Liping SuDepartment of Radiology, The Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Yuwei XiaHuiying Medical Technology Co., Ltd, Dongsheng Science and Technology Park, Beijing, China.
Quan YangDepartment of Radiology, The Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Dan LiuDepartment of Radiology, The Yongchuan Hospital of Chongqing Medical University, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo identify the value of radiomics method derived from CT images to predict prognosis in patients with COVID-19.

methodsA total of 40 patients with COVID-19 were enrolled in the study. Baseline clinical data, CT images, and laboratory testing results were collected from all patients. We defined that ROIs in the absorption group decreased in the density and scope in GGO, and ROIs in the progress group progressed to consolidation. A total of 180 ROIs from absorption group (

resultsA total of 15 radiomics features with respective coefficients were calculated. The AUC values of radiomics models (kNN, SVM, and LR) were 0.88, 0.88, and 0.84, respectively, showing a good performance. The C-index of the clinical factors model was 0.82 [95% CI (0.75-0.88)] in the training set and 0.77 [95% CI (0.59-0.90)] in the validation set. The radiomics nomogram showed optimal prediction performance. In the training set, the C-index was 0.91 [95% CI (0.85-0.95)], and in the validation set, the C-index was 0.85 [95% CI (0.69-0.95)]. For the training set, the C-index of the radiomics nomogram was significantly higher than the clinical factors model (

conclusionsThe radiomics nomogram based on CT images showed favorable prediction performance in the prognosis of COVID-19. The radiomics nomogram could be used as a potential biomarker for more accurate categorization of patients into different stages for clinical decision-making process. ADVANCES IN KNOWLEDGE: Radiomics features based on chest CT images help clinicians to categorize the patients of COVID-19 into different stages. Radiomics nomogram based on CT images has favorable predictive performance in the prognosis of COVID-19. Radiomics act as a potential modality to supplement conventional medical examinations.

Indexed as

NomogramsTomography, X-Ray ComputedAdultCOVID-19FemaleHumansMaleMiddle AgedPredictive Value of TestsPrognosisRandom AllocationRetrospective Studies

Identifiers

PMID33296222
PMCPMC7774709

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.