Evidence map›Paper›PMID 33296054›Full record

ArticleEJNMMI physics2020

Kidney dosimetry in 777 patients during

Mattias Sandström, Nanette Freedman, Katarzyna Fröss-Baron, Tanweera Kahn, Anders Sundin

Abstract read
In one paragraph

Article in EJNMMI physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Dosimetry of [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Pooled it
  2. Article
  3. Outcome-driven dosimetry optimization for [European journal of nuclear medicine and molecular imaging · 2026
    Article
  4. Article
  5. Review
  6. Validation of Simplified Renal Dosimetry Protocols forMolecular imaging and radionuclide therapy · 2026
    Article
  7. Continuous βClinical and translational radiation oncology · 2025
    Article
  8. Article
  9. Article
  10. Dosimetry Software for Theranostic Applications: Current Capabilities and Future Prospects.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Review
  11. Article
  12. Article
  13. Estimation of kidney doses from [EJNMMI physics · 2024
    Article
  14. Review
  15. Prediction of [EJNMMI physics · 2024
    Article
  16. Review
  17. Single-Time-Point Imaging for Dosimetry After [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  18. Article
  19. Review
  20. Theranostics and Patient-Specific Dosimetry.Seminars in radiation oncology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mattias SandströmSection of Nuclear Medicine and PET, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden. mattias.sandstrom@akademiska.se.ORCID http://orcid.org/0000-0002-5443-3122
Nanette FreedmanInstitute of Nuclear Medicine, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Katarzyna Fröss-BaronDivision of Endocrine Oncology, Department of Medical Sciences, Uppsala University Hospital, Uppsala, Sweden.
Tanweera KahnSection of Oncology, Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Anders SundinSection of Nuclear Medicine and PET, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeFractionated peptide receptor radionuclide therapy (PRRT) with

methodsIn 777 patients with disseminated neuroendocrine tumors undergoing PRRT, SPECT/CT over the abdomen was acquired at 1, 4, and 7 days after

resultsThe fractional contributions from extrapolations before day 1 measurement and after day 7 measurement were approximately 26% and 11%, respectively. The mean differences in absorbed dose, based on one, two, and three time points were small, but with high method dependence for individual patients. The differences in estimated t

conclusionWhen assessing simplifications of methods for calculation of the absorbed dose to the kidneys, it was of the uttermost importance to incorporate the fractional contribution for the extrapolations included in the reference method. Measurements at an early and a late time point were found most important. An intermediate measurement contributes with an idea of the goodness of the fit.

Indexed as

177Lu-DOTATATEDosimetryExtrapolationKidneyNeuroendocrine tumorsSimplifications

Identifiers

PMID33296054
PMCPMC7726073

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.