Evidence map›Paper›PMID 33296050›Full record

ArticleEJNMMI physics2020

Tumor response prediction in

Lise Wei, Can Cui, Jiarui Xu, Ravi Kaza, Issam El Naqa, Yuni K Dewaraja

Open access · goldAbstract read
In one paragraph

Article in EJNMMI physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Applications of artificial intelligence in nuclear medicine.Zeitschrift fur medizinische Physik · 2026
    Review
  3. Japanese journal of radiology · 2026
    Article
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Lise WeiApplied Physics Program, University of Michigan, Ann Arbor, MI, USA.ORCID http://orcid.org/0000-0001-7226-2091
Can CuiDepartment of Electrical Engineering, University of Michigan, Ann Arbor, MI, USA.
Jiarui XuDepartment of Electrical Engineering, University of Michigan, Ann Arbor, MI, USA.
Ravi KazaDepartment of Radiology, University of Michigan, Ann Arbor, MI, USA.
Issam El NaqaApplied Physics Program, University of Michigan, Ann Arbor, MI, USA.
Yuni K DewarajaDepartment of Radiology, University of Michigan, Ann Arbor, MI, USA. liswei@umich.edu.
University of Michigan · US

Funding

Imaging and Dosimetry of Yttrium-90 for Personalized Cancer TreatmentR01EB022075 · NIBIB · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DEWARAJA, YUNI K · 2016 to 2023
$4.7M
Optimal Decision Making in Radiotherapy Using Panomics AnalyticsR01CA233487 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI EL NAQA, ISSAM M. · 2019 to 2023
$2.4M
NCI NIH HHS R01-CA233487NIBIB NIH HHS R01 EB022075NIBIB NIH HHS R01-EB022075
6 · The paper itself

Abstract

purposeTo evaluate whether lesion radiomics features and absorbed dose metrics extracted from post-therapy

resultsThe phantom study identified 15/46 reproducible and robust radiomics features that were subsequently used in the patient models. A lesion response model with zone percentage (ZP) and mean absorbed dose achieved an AUC of 0.729 (95% CI 0.702-0.758), and a progression model with zone size nonuniformity (ZSN) and absorbed dose achieved a c-index of 0.803 (95% CI 0.790-0.815) on nested cross-validation (CV). Although the combined models outperformed the radiomics only and absorbed dose only models, statistical significance was not achieved with the current limited data set to establish expected superiority.

conclusionWe have developed new lesion-level response and progression models using textural radiomics features, derived from

Indexed as

90YAbsorbed doseLiver cancerPET imagingRadioembolizationRadiomics

Identifiers

PMID33296050
PMCPMC7726084
OpenAlexW3112134892

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.