Evidence map›Paper›PMID 33295874›Full record

ArticleeLife2020

PRD-2 directly regulates

Christina M Kelliher, Randy Lambreghts, Qijun Xiang, Christopher L Baker, Jennifer J Loros, Jay C Dunlap

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. A Compensated Clock: Temperature and Nutritional Compensation Mechanisms Across Circadian Systems.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
  4. Review
  5. The auxotrophicFungal genetics reports · 2024
    Article
  6. Article
  7. A conditionalScience advances · 2023
    Article
  8. Review
  9. Article
  10. PRD-2 mediates clock-regulated perinuclear localization of clock gene RNAs within the circadian cycle ofProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Christina M KelliherDepartment of Molecular & Systems Biology, Geisel School of Medicine at Dartmouth, Hanover, United States.ORCID 0000-0002-4554-1818
Randy LambreghtsDepartment of Molecular & Systems Biology, Geisel School of Medicine at Dartmouth, Hanover, United States.
Qijun XiangDepartment of Molecular & Systems Biology, Geisel School of Medicine at Dartmouth, Hanover, United States.
Christopher L BakerDepartment of Molecular & Systems Biology, Geisel School of Medicine at Dartmouth, Hanover, United States.
Jennifer J LorosDepartment of Biochemistry & Cell Biology, Geisel School of Medicine at Dartmouth, Hanover, United States.
Jay C DunlapDepartment of Molecular & Systems Biology, Geisel School of Medicine at Dartmouth, Hanover, United States.ORCID 0000-0003-1577-0457
Dartmouth College · US

Funding

Genetic and Molecular Dissection of the Neurospora ClockR35GM118021 · NIGMS · DARTMOUTH COLLEGE · PI Jay C. Dunlap · 2016 to 2026
$7.3M
Identification and Analysis of Circadian Clock-Controlled GenesR35GM118022 · NIGMS · DARTMOUTH COLLEGE · PI LOROS, JENNIFER J. · 2016 to 2021
$3.7M
Genetic and Molecular Dissection of Regulatory Mechanisms Underlying Temperature and Nutritional Compensation of the Circadian Clock in Neurospora crassaF32GM128252 · NIGMS · DARTMOUTH COLLEGE · PI KELLIHER, CHRISTINA · 2018 to 2022
$210k
EMSL 50173NIGMS NIH HHS F32 GM128252NIGMS NIH HHS R35 GM118021NIGMS NIH HHS R35 GM118022
6 · The paper itself

Abstract

Circadian clocks in fungi and animals are driven by a functionally conserved transcription-translation feedback loop. In

Indexed as

Casein Kinase ICircadian ClocksFungal ProteinsGene Expression Regulation, FungalGenes, FungalNeurospora crassaCasein Kinase IFungal ProteinsCasein Kinase Icircadian clockgeneticsgenomicsN. crassaneurosporanonsense mediated decayprd-2, upf1 / prd-6RNA-binding proteinSUZ domain

Identifiers

PMID33295874
PMCPMC7746235
OpenAlexW3111281648

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.