Evidence map›Paper›PMID 33295453›Full record

ArticleArquivos brasileiros de cardiologia2020

Microvascular Reactivity in Hypertensive Patients with High Body Adiposity.

Jenifer d'El-Rei, Michelle Rabello Cunha, Samanta de Souza Mattos, Bianca Cristina Marques, Viviane Prangiel de Menezes, Ana Rosa Cunha, Érica Monteiro França, Wille Oigman, Mario Fritsch Neves

Abstract read
In one paragraph

Article in Arquivos brasileiros de cardiologia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Jenifer d'El-ReiUniversidade do Estado do Rio de Janeiro - Clínica Médica, Rio de Janeiro, RJ - Brasil.
Michelle Rabello CunhaUniversidade do Estado do Rio de Janeiro - Clínica Médica, Rio de Janeiro, RJ - Brasil.
Samanta de Souza MattosUniversidade do Estado do Rio de Janeiro - Clínica Médica, Rio de Janeiro, RJ - Brasil.
Bianca Cristina MarquesUniversidade do Estado do Rio de Janeiro - Clínica Médica, Rio de Janeiro, RJ - Brasil.
Viviane Prangiel de MenezesUniversidade do Estado do Rio de Janeiro - Clínica Médica, Rio de Janeiro, RJ - Brasil.
Ana Rosa CunhaUniversidade do Estado do Rio de Janeiro - Clínica Médica, Rio de Janeiro, RJ - Brasil.
Érica Monteiro FrançaUniversidade do Estado do Rio de Janeiro - Clínica Médica, Rio de Janeiro, RJ - Brasil.
Wille OigmanUniversidade do Estado do Rio de Janeiro - Clínica Médica, Rio de Janeiro, RJ - Brasil.
Mario Fritsch NevesUniversidade do Estado do Rio de Janeiro - Clínica Médica, Rio de Janeiro, RJ - Brasil.ORCID 0000-0002-0797-572X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeveral anthropometric indexes have been proposed to determine the association between overweight and cardiovascular risk factors.

objectiveTo evaluate the relationship between body adiposity and microvascular reactivity in hypertensive patients under antihypertensive therapy.

methodsTreated hypertensive patients aged 40 to 70 were submitted to evaluation of anthropometric indexes: conicity (CI), body adiposity (BAI), visceral adiposity (VAI) and waist-to-height ratio (WHtR). Participants were divided by the terciles of fat percentage (%F) obtained by bioelectrical impedance. The patients underwent microvascular reactivity test (Laser Speckle Contrast Image) and pulse wave velocity (PWV) measurement. The p value <0.05 was considered statistically significant.

resultsThe variation of the area under the curve (AUC) of the skin perfusion was lower in the upper tercile (97±57% vs. 67±36%; p=0.027). %F showed significant correlation with WHtR (r=0.77; p<0.001), VAI (r=0.41; p=0.018), CI (r=0.60; p<0.001), BAI (r=0.65; p<0.001) in men and only with WHtR (r=0.55; p<0.001) and BAI (r=0.60; p<0.001) in women. In linear regression, AUC was independently associated with %F (β=-3.15; p=0.04) in women and with blood glucose (β=-1.15; p=0.02) in men. There was no difference in PWV measurements.

conclusionAnthropometric indices were more associated with %F in men. Higher body adiposity was associated with lower microvascular reactivity, which was more evident in women. There was no difference in arterial stiffness, which may have been influenced by antihypertensive treatment.

Indexed as

AdiposityPulse Wave AnalysisAdultAgedBody Mass IndexCross-Sectional StudiesFemaleHumansMaleMiddle AgedRisk FactorsWaist Circumference

Identifiers

PMID33295453
PMCPMC8452213

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.