Evidence map›Paper›PMID 33295442›Full record

ArticleArquivos brasileiros de cardiologia2020

Pulmonary Vascular Volume Estimated by Automated Software is a Mortality Predictor after Acute Pulmonary Embolism.

Leonardo Soriano, Marcel Koenigkam Santos, Danilo Tadeu Wada, Kelvin Vilalva, Talita Tavares Castro, Oliver Weinheimer, Valdair Francisco Muglia, Antonio Pazin Filho, Carlos Henrique Miranda

Open access · diamondAbstract read
In one paragraph

Article in Arquivos brasileiros de cardiologia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Leonardo SorianoUniversidade de São Paulo Faculdade de Medicina de Ribeirão Preto - Divisão de Medicina de Emergência do Departamento de Clínica Médica, Ribeirão Preto, SP - Brasil.
Marcel Koenigkam SantosUniversidade de São Paulo Faculdade de Medicina de Ribeirão Preto - Divisão de Radiologia do Departamento de Imagens Médicas, Hematologia e Oncologia Clínica, Ribeirão Preto, SP - Brasil.ORCID 0000-0002-7160-4691
Danilo Tadeu WadaUniversidade de São Paulo Faculdade de Medicina de Ribeirão Preto - Divisão de Radiologia do Departamento de Imagens Médicas, Hematologia e Oncologia Clínica, Ribeirão Preto, SP - Brasil.ORCID 0000-0002-6433-4849
Kelvin VilalvaUniversidade de São Paulo Faculdade de Medicina de Ribeirão Preto - Divisão de Medicina de Emergência do Departamento de Clínica Médica, Ribeirão Preto, SP - Brasil.
Talita Tavares CastroUniversidade de São Paulo Faculdade de Medicina de Ribeirão Preto - Divisão de Medicina de Emergência do Departamento de Clínica Médica, Ribeirão Preto, SP - Brasil.
Oliver WeinheimerUniversity Hospital Heidelberg - Department of Diagnostic and Interventional Radiology and Translational Lung Research Centre Heidelberg (TLRC) - German Lung Research Centre (DZL), Heidelberg - Alemanha.
Valdair Francisco MugliaUniversidade de São Paulo Faculdade de Medicina de Ribeirão Preto - Divisão de Radiologia do Departamento de Imagens Médicas, Hematologia e Oncologia Clínica, Ribeirão Preto, SP - Brasil.
Antonio Pazin FilhoUniversidade de São Paulo Faculdade de Medicina de Ribeirão Preto - Divisão de Medicina de Emergência do Departamento de Clínica Médica, Ribeirão Preto, SP - Brasil.
Carlos Henrique MirandaUniversidade de São Paulo Faculdade de Medicina de Ribeirão Preto - Divisão de Medicina de Emergência do Departamento de Clínica Médica, Ribeirão Preto, SP - Brasil.ORCID 0000-0002-5968-4879
Universidade de Ribeirão Preto · BRHeidelberg University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute pulmonary embolism (APE) has a variable clinical outcome. Computed tomography pulmonary angiography (CTPA) is the gold standard for this diagnosis.

objectiveTo evaluate if the pulmonary vascular volume (PVV) quantified by automated software is a mortality predictor after APE.

methodsRetrospective cohort study where the CTPA imaging of 61 patients with APE was reanalyzed. Pulmonary vascular volume (PVV) and pulmonary volume (PV) were automatically estimated using the Yacta software. We calculated the adjusted PVV by the ratio: PVV(cm3)/PV(liters). Classical prognostic CTPA parameters (clot load index, right ventricle/left ventricle diameter ratio, pulmonary artery/aorta diameter ratio, ventricular septal bowing, pulmonary infarction and reflux of contrast into the hepatic vein) were assessed. The outcome assessed was one-month mortality. We considered a p-value <0.05 as statistically significant.

resultsSeven deaths (11%) occurred at one month among these 61 patients. PVV<23cm3/L was an independent predictor of one-month mortality in the univariate [odds ratio (OR): 26; 95% confidence interval (CI): 3-244; p=0.004] and multivariate analyses [adjusted OR: 19; 95%CI: 1.3-270; p=0.03]. The classical CTPA parameters were not associated with one-month mortality in this sample. The PVV<23cm3/L showed a sensitivity of 86%, a specificity of 82%, a negative predictive value of 94% and a positive predictive value of 64% to identify the patients who died.

conclusionPVV<23cm3/L was an independent predictor of one-month mortality after APE. This parameter showed better prognostic performance than other classical CTPA findings. (Arq Bras Cardiol. 2020; 115(5):809-818).

Indexed as

Pulmonary EmbolismAcute DiseaseAngiographyHumansPulmonary ArteryRetrospective StudiesSoftware

Identifiers

PMID33295442
PMCPMC8452195
OpenAlexW3107713462

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.