Evidence map›Paper›PMID 33295136›Full record

Observational studyCancer reports (Hoboken, N.J.)2021

Quality of life and factors affecting it in adult cancer patients undergoing cancer chemotherapy in a tertiary care hospital.

Saravana Kumar Ramasubbu, Rajesh K Pasricha, Uttam K Nath, Vikram Singh Rawat, Biswadeep Das

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in Cancer reports (Hoboken, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 2 pooled it
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 2 syntheses or guidelines pooled it, 88 citations in OpenAlex.

  1. Pooled it
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  6. Article
  7. Article
  8. Quality of Life and Symptoms of Anxiety and Depression Among Patients With Cancer: Insights From a Tertiary Care Hospital.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Article
  9. Article
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  11. Predicting health-related quality of life two years post-diagnosis across seven cancer types: using machine learning to identify vulnerable patients.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
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  19. Mapping cancer patient online support groups: enhancing patient care in a low-middle income healthcare system.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Review
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Saravana Kumar RamasubbuDepartment of Pharmacology, All India Institute of Medical Sciences(AIIMS), Rishikesh, India.
Rajesh K PasrichaDepartment of Radiation Oncology, All India Institute of Medical Sciences(AIIMS), Rishikesh, India.
Uttam K NathDepartment of Hemato-Oncology, All India Institute of Medical Sciences(AIIMS), Rishikesh, India.
Vikram Singh RawatDepartment of Psychiatry, All India Institute of Medical Sciences(AIIMS), Rishikesh, India.
Biswadeep DasDepartment of Pharmacology, All India Institute of Medical Sciences(AIIMS), Rishikesh, India.ORCID 0000-0002-3222-2527
All India Institute of Medical Sciences Rishikesh · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCancer is the second most common cause of deaths worldwide. Likewise, in India, it is a major health problem, and disease burden is escalating every year. Cancer chemotherapy produces unfavorable effects on the well-being of an individual. Since the past few years, quality of life (QoL) is considered as the main goal of cancer treatment in the survival of a patient.

aimThis current study aimed to assess the QoL and factors affecting it in adult cancer patients undergoing chemotherapy treatment. METHODS AND

resultsAn analytical, cross-sectional study was conducted to achieve the objectives, employing the consecutive sampling method. A total of 120 adult (>19 years) patients were recruited from daycare chemotherapy unit of a tertiary care hospital. The data were collected using patient record form and Functional Assessment of Cancer Therapy-General (FACT-G), a quality of life (QoL) questionnaire. The overall mean score of quality of life (QoL) was 61.933 ± 5.85502. The domains of functional well-being and emotional well-being were most negatively affected after cancer chemotherapy. Education (illiteracy) and occupation (unemployment) were negatively associated with overall quality of life (QoL) of cancer patients on chemotherapy. Adverse drug reactions due to cancer chemotherapy negatively affect the quality of life (QoL) of cancer patients. Education (illiteracy) affects social well-being domain of cancer patients. Working in the government/private sector has a positive impact on functional well-being domain of quality of life (QoL).

conclusionThe study findings suggest an overall low quality of life (QoL) among adult cancer patients undergoing chemotherapy at our setup. It has been identified as a stressful therapy, also affecting both psychological and physical well-being. Poor infrastructure, illiteracy, poverty, and lack of proper treatment facilities at most centres often lead to poor survival outcomes and hence focus has always been on achieving quantity of life rather than quality of life (QoL). This is further complicated due to nonavailability of validated tools in local vernacular, apathy of the treating physicians in the context of QoL aspects and social and cultural factors that are unique to this society. Psycho-oncology needs to become an integral entity of comprehensive cancer care.

Indexed as

Quality of LifeAdultAntineoplastic AgentsCross-Sectional StudiesEducational StatusFemaleHumansIndiaMaleMiddle AgedNeoplasmsSurveys and QuestionnairesSurvival AnalysisTertiary Care CentersYoung AdultAntineoplastic Agentscancer chemotherapydomainsFACT-Gquality of life (QoL)tertiary care hospital

Identifiers

PMID33295136
PMCPMC8451381
OpenAlexW3110712544

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.