Evidence map›Paper›PMID 33295067›Full record

ArticleESC heart failure2021

Impaired cerebral oxygenation in heart failure patients at rest and during head-up tilt testing.

Isabella Kharraziha, Hannes Holm, Martin Magnusson, Per Wollmer, John Molvin, Amra Jujic, Artur Fedorowski, Erasmus Bachus, Viktor Hamrefors

Open access · goldAbstract read
In one paragraph

Article in ESC heart failure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Isabella KharrazihaDepartment of Clinical Sciences, Lund University, Malmö, 20213, Sweden.
Hannes HolmDepartment of Clinical Sciences, Lund University, Malmö, 20213, Sweden.
Martin MagnussonDepartment of Clinical Sciences, Lund University, Malmö, 20213, Sweden.
Per WollmerDepartment of Translational Medicine, Lund University, Malmö, Sweden.
John MolvinDepartment of Clinical Sciences, Lund University, Malmö, 20213, Sweden.
Amra JujicDepartment of Clinical Sciences, Lund University, Malmö, 20213, Sweden.
Artur FedorowskiDepartment of Clinical Sciences, Lund University, Malmö, 20213, Sweden.
Erasmus BachusDepartment of Clinical Sciences, Lund University, Malmö, 20213, Sweden.
Viktor HamreforsDepartment of Clinical Sciences, Lund University, Malmö, 20213, Sweden.
Lund University · SESkåne University Hospital · SEMalmö University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsHeart failure (HF) confers potentially negative effects on the brain and autonomic nervous system. The measurement cerebral tissue oxygen saturation (SctO METHODS AND

resultsNon-invasive haemodynamic monitoring and near-infrared spectroscopy were applied during head-up tilt (HUT) in 61 HF patients [mean (SD) 71 (11) years, 82% male, New York Heart Association (NYHA) class I-III] and 60 controls [60 (12) years, 42% male). Group differences in continuous variables were compared using Student's t-test. Associations between HF and SctO

conclusionsCerebral tissue oxygenation is lower in HF patients both at rest and during orthostasis compared with subjects without HF. Future studies should test if the lower cerebral oxygenation associates with negative prognosis and with impaired cognitive function.

Indexed as

Heart FailureTilt-Table TestAutonomic Nervous SystemBlood PressureFemaleHeart RateHumansMaleCerebral oximetryHead-up tilt testHeart failureOrthostatic provocation

Identifiers

PMID33295067
PMCPMC7835614
OpenAlexW3113304890

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.