Evidence map›Paper›PMID 33294978›Full record

Observational studyCancer2021

Racial disparities in patients with coronavirus disease 2019 infection and gynecologic malignancy.

Olivia D Lara, Maria J Smith, Yuyan Wang, Roisin O'Cearbhaill, Stephanie V Blank, Valentin Kolev, Caitlin Carr, Anne Knisely, Jennifer McEachron, Lisa Gabor and 8 more

Abstract readMulticenter StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. High Risk of Heart Tumors after COVID-19.Life (Basel, Switzerland) · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Olivia D LaraDepartment of Obstetrics and Gynecology, Division of Gynecologic Oncology, Perlmutter Cancer Center, New York University (NYU) Langone Health, New York, New York.ORCID 0000-0002-3540-5804
Maria J SmithDepartment of Obstetrics and Gynecology, Division of Gynecologic Oncology, Perlmutter Cancer Center, New York University (NYU) Langone Health, New York, New York.ORCID 0000-0002-9742-5675
Yuyan WangDepartment of Population Health, NYU Langone Health, New York, New York.
Roisin O'CearbhaillDepartment of Medical Oncology, Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, New York, New York.
Stephanie V BlankDepartment of Obstetrics, Gynecologic and Reproductive Science, Division of Gynecologic Oncology, Icahn School of Medicine at Mount Sinai, New York, New York.
Valentin KolevDepartment of Obstetrics, Gynecologic and Reproductive Science, Division of Gynecologic Oncology, Icahn School of Medicine at Mount Sinai, New York, New York.
Caitlin CarrDepartment of Obstetrics, Gynecologic and Reproductive Science, Division of Gynecologic Oncology, Icahn School of Medicine at Mount Sinai, New York, New York.
Anne KniselyDepartment of Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia University, New York, New York.
Jennifer McEachronDepartment of Obstetrics and Gynecology, State University of New York Downstate Medical Center, Brooklyn, New York.
Lisa GaborDepartment of Obstetrics and Gynecology and Women's Health, Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, New York.
Eloise Chapman-DavisDepartment of Obstetrics and Gynecology, Cornell University, New York, New York.
Justin JeeDepartment of Population Health, NYU Langone Health, New York, New York.
Julia FehnigerDepartment of Obstetrics and Gynecology, Division of Gynecologic Oncology, Perlmutter Cancer Center, New York University (NYU) Langone Health, New York, New York.
Yi-Chun LeeDepartment of Obstetrics and Gynecology, State University of New York Downstate Medical Center, Brooklyn, New York.
Sara IsaniDepartment of Obstetrics and Gynecology and Women's Health, Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, New York.
Mengling LiuDepartment of Population Health, NYU Langone Health, New York, New York.
Jason D WrightDepartment of Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia University, New York, New York.
Bhavana PothuriDepartment of Obstetrics and Gynecology, Division of Gynecologic Oncology, Perlmutter Cancer Center, New York University (NYU) Langone Health, New York, New York.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

backgroundMounting evidence suggests disproportionate coronavirus disease 2019 (COVID-19) hospitalizations and deaths because of racial disparities. The association of race in a cohort of gynecologic oncology patients with severe acute respiratory syndrome-coronavirus 2 infection is unknown.

methodsData were abstracted from gynecologic oncology patients with COVID-19 infection among 8 New York City area hospital systems. A multivariable mixed-effects logistic regression model accounting for county clustering was used to analyze COVID-19-related hospitalization and mortality.

resultsOf 193 patients who had gynecologic cancer and COVID-19, 67 (34.7%) were Black, and 126 (65.3%) were non-Black. Black patients were more likely to require hospitalization compared with non-Black patients (71.6% [48 of 67] vs 46.0% [58 of 126]; P = .001). Of 34 (17.6%) patients who died from COVID-19, 14 (41.2%) were Black. Among those who were hospitalized, compared with non-Black patients, Black patients were more likely to: have ≥3 comorbidities (81.1% [30 of 37] vs 59.2% [29 of 49]; P = .05), to reside in Brooklyn (81.0% [17 of 21] vs 44.4% [12 of 27]; P = .02), to live with family (69.4% [25 of 36] vs 41.6% [37 of 89]; P = .009), and to have public insurance (79.6% [39 of 49] vs 53.4% [39 of 73]; P = .006). In multivariable analysis, among patients aged <65 years, Black patients were more likely to require hospitalization compared with non-Black patients (odds ratio, 4.87; 95% CI, 1.82-12.99; P = .002).

conclusionsAlthough Black patients represented only one-third of patients with gynecologic cancer, they accounted for disproportionate rates of hospitalization (>45%) and death (>40%) because of COVID-19 infection; younger Black patients had a nearly 5-fold greater risk of hospitalization. Efforts to understand and improve these disparities in COVID-19 outcomes among Black patients are critical.

Indexed as

Health Status DisparitiesAdultAgedBlack or African AmericanCOVID-19FemaleGenital Neoplasms, FemaleHospitalizationHumansLogistic ModelsMiddle AgedMultivariate AnalysisNew York CityRetrospective StudiesRisk FactorsSARS-CoV-2coronavirus disease 2019 (COVID-19)gynecologic canceroutcomesracial disparitiessevere acute respiratory syndrome-coronavirus 2 (SARS-CoV-2)

Identifiers

PMID33294978
PMCPMC8504148

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.