Evidence map›Paper›PMID 33294783›Full record

ArticleiScience2020

Single-Cell Transcriptome Analysis Dissects the Replicating Process of Pancreatic Beta Cells in Partial Pancreatectomy Model.

Hisato Tatsuoka, Satoko Sakamoto, Daisuke Yabe, Ryotaro Kabai, Unyanee Kato, Tatsuya Okumura, Ainur Botagarova, Shinsuke Tokumoto, Ryota Usui, Masahito Ogura and 5 more

Open access · goldAbstract read
In one paragraph

Article in iScience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. β-Cell Heterogeneity and Plasticity.Advances in anatomy, embryology, and cell biology · 2024
    Review
  7. β-Cell Regeneration Is Driven by Pancreatic Plasticity.Advances in anatomy, embryology, and cell biology · 2024
    Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Hisato TatsuokaDepartment of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Satoko SakamotoMedical Innovation Center, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Daisuke YabeDepartment of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Ryotaro KabaiMedical Innovation Center, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Unyanee KatoMedical Innovation Center, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Tatsuya OkumuraMedical Innovation Center, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Ainur BotagarovaDepartment of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Shinsuke TokumotoDepartment of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Ryota UsuiDepartment of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Masahito OguraDepartment of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Kazuaki NagashimaDepartment of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Eri MukaiLaboratory of Medical Physiology and Metabolism, Department of Biomedical Sciences, College of Life Sciences, Ritsumeikan University, Shiga, Japan.
Yoshio FujitaniLaboratory of Developmental Biology and Metabolism, Institute for Molecular & Cellular Regulation, Gunma University, Gunma, Japan.
Akira WatanabeMedical Innovation Center, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Nobuya InagakiDepartment of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Kyoto University · JPGunma University · JPRitsumeikan University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heterogeneity of gene expression and rarity of replication hamper molecular analysis of β-cell mass restoration in adult pancreas. Here, we show transcriptional dynamics in β-cell replication process by single-cell RNA sequencing of murine pancreas with or without partial pancreatectomy. We observed heterogeneity of

Indexed as

Biological SciencesGenomicsMolecular Biology

Identifiers

PMID33294783
PMCPMC7689163
OpenAlexW3095668982

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.