Evidence map›Paper›PMID 33294468›Full record

ReviewJournal of immunology research2020

Cells of the Innate and Adaptive Immune Systems in Kaposi's Sarcoma.

Owen Ngalamika, Sody Munsaka

Open access · goldAbstract readReview
In one paragraph

Review in Journal of immunology research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Expression of CD40L on CD4Cancer treatment and research communications · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Owen NgalamikaDermatology and Venereology Division, University Teaching Hospital, University of Zambia School of Medicine, Lusaka, Zambia.ORCID https://orcid.org/0000-0002-0648-4128
Sody MunsakaDepartment of Biomedical Sciences, School of Health Sciences, University of Zambia, Lusaka, Zambia.
University of Zambia · ZMUniversity Teaching Hospital · ZM

Funding

Biomarkers of Kaposi sarcoma recrudescence in ZambiaK43TW011095 · FIC · UNIVERSITY OF ZAMBIA · PI NGALAMIKA, OWEN · 2018 to 2023
$721k
FIC NIH HHS K43 TW011095
6 · The paper itself

Abstract

Kaposi's sarcoma (KS) is an angioproliferative malignancy whose associated etiologic agent is the Kaposi's sarcoma-associated herpesvirus (KSHV). KS is the most prevalent malignancy among HIV-infected individuals globally and is considered an AIDS-defining malignancy. The different forms of KS including HIV-associated KS, iatrogenic (immunosuppression-related) KS, and classical KS in elderly males suggest that immune cell dysregulation is among the key components in promoting KS development in KSHV-infected individuals. It is therefore expected that different cell types of the immune system likely play distinct roles in promoting or inhibiting KS development. This narrative review is focused on discussing cells of the innate and adaptive immune systems in KSHV infection and KS pathogenesis, including how these cells can be useful in the control of KSHV infection and treatment of KS.

Indexed as

Adaptive ImmunityImmunity, InnateAnimalsCell Transformation, ViralCombined Modality TherapyDisease SusceptibilityHerpesviridae InfectionsHerpesvirus 8, HumanHumansImmune SystemImmunomodulationMolecular Targeted TherapySarcoma, KaposiTumor Microenvironment

Identifiers

PMID33294468
PMCPMC7700054
OpenAlexW3109513602

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.