Evidence map›Paper›PMID 33294466›Full record

ArticleJournal of immunology research2020

Effect of SIS3 on Extracellular Matrix Remodeling and Repair in a Lipopolysaccharide-Induced ARDS Rat Model.

Qiong Liang, Qiqing Lin, Yueyong Li, Weigui Luo, Xia Huang, Yujie Jiang, Chunyan Qin, Jin Nong, Xiang Chen, Suren Rao Sooranna and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

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  13. Biomedicines · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Qiong LiangThe First Clinical Medical College of Jinan University, Guangzhou City, Guangdong Province, China.
Qiqing LinThe First Clinical Medical College of Jinan University, Guangzhou City, Guangdong Province, China.
Yueyong LiThe First Clinical Medical College of Jinan University, Guangzhou City, Guangdong Province, China.
Weigui LuoDepartment of Respiratory Medicine, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise City, Guangxi Province, China.
Xia HuangDepartment of Respiratory Medicine, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise City, Guangxi Province, China.
Yujie JiangDepartment of Respiratory Medicine, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise City, Guangxi Province, China.
Chunyan QinDepartment of Respiratory Medicine, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise City, Guangxi Province, China.
Jin NongIntensive Care Unit, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise City, Guangxi Province, China.
Xiang ChenIntensive Care Unit, People's Hospital of Guangxi Zhuang Autonomous Region, Nanning City, Guangxi Province, China.
Suren Rao SoorannaDepartment of Metabolism, Digestion and Reproduction, Imperial College London, Chelsea & Westminster Hospital, 369 Fulham Road London, SW10 9NH, UK.
Liao PinhuIntensive Care Unit, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise City, Guangxi Province, China.ORCID https://orcid.org/0000-0003-1109-675X
Affiliated Hospital of Youjiang Medical University for Nationalities · CNJinan University · CNChelsea and Westminster Hospital · GBThe People's Hospital of Guangxi Zhuang Autonomous Region · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The remodeling of the extracellular matrix (ECM) in the parenchyma plays an important role in the development of acute respiratory distress syndrome (ARDS), a disease characterized by lung injury. Although it is clear that TGF-

Indexed as

AnimalsBiomarkersCollagenDisease Models, AnimalExtracellular MatrixGene ExpressionIsoquinolinesLipopolysaccharidesMatrix Metalloproteinase 2Matrix Metalloproteinase 9NeutrophilsPyridinesPyrrolesRatsReceptor for Advanced Glycation End ProductsRespiratory Distress Syndrome6,7-dimethyl-2-(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo(2,3-b)pyridin-3-yl-prop-2-enoyl)-1,2,3,4-tetrahydroisoquinoline hydrochlorideBiomarkersCollagenIsoquinolinesLipopolysaccharidesMatrix Metalloproteinase 2Matrix Metalloproteinase 9PyridinesPyrrolesReceptor for Advanced Glycation End ProductsSmad3 ProteinTransforming Growth Factor beta1

Identifiers

PMID33294466
PMCPMC7714568
OpenAlexW3108091923

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.