Evidence map›Paper›PMID 33294452›Full record

ArticleBioMed research international2020

The Neutrophil Percentage-to-Albumin Ratio as a New Predictor of All-Cause Mortality in Patients with Cardiogenic Shock.

Yue Yu, Yu Liu, Xinyu Ling, Renhong Huang, Suyu Wang, Jie Min, Jian Xiao, Yufeng Zhang, Zhinong Wang

Abstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. The role of neutrophils in vasospasm and delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage: Is it time for a SAH clinical trial targeting neutrophils?Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2025
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yue YuDepartment of Cardiothoracic Surgery, Changzheng Hospital, Naval Medical University, Shanghai 200003, China.ORCID https://orcid.org/0000-0002-7960-3968
Yu LiuDepartment of Gastroenterology, Jinling Hospital, No. 305 Zhongshan East Road, Nanjing, 210002 Jiangsu, China.ORCID https://orcid.org/0000-0001-5134-5808
Xinyu LingDepartment of Cardiothoracic Surgery, Changzheng Hospital, Naval Medical University, Shanghai 200003, China.ORCID https://orcid.org/0000-0002-6550-4192
Renhong HuangDepartment of General Surgery, Changzheng Hospital, Naval Medical University, Shanghai 200003, China.ORCID https://orcid.org/0000-0001-9342-2031
Suyu WangDepartment of Cardiothoracic Surgery, Changzheng Hospital, Naval Medical University, Shanghai 200003, China.
Jie MinBethune International Peace Hospital, Shijiazhuang 050082, China.ORCID https://orcid.org/0000-0002-9999-7810
Jian XiaoDepartment of Cardiothoracic Surgery, Changzheng Hospital, Naval Medical University, Shanghai 200003, China.ORCID https://orcid.org/0000-0002-9237-707X
Yufeng ZhangDepartment of Cardiothoracic Surgery, Changzheng Hospital, Naval Medical University, Shanghai 200003, China.ORCID https://orcid.org/0000-0003-0236-6121
Zhinong WangDepartment of Cardiothoracic Surgery, Changzheng Hospital, Naval Medical University, Shanghai 200003, China.ORCID https://orcid.org/0000-0001-6308-7949

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough the neutrophil percentage-to-albumin ratio (NPAR) has proven to be a robust systemic inflammation-based predictor of mortality in a wide range of diseases, the prognostic value of the NPAR in critically ill patients with cardiogenic shock (CS) remains unknown. This study aimed at investigating the association between the admission NPAR and clinical outcomes in CS patients using real-world data.

methodsCritically ill patients diagnosed with CS in the Medical Information Mart for Intensive Care-III (MIMIC-III) database were included in our study. The study endpoints included all-cause in-hospital, 30-day, and 365-day mortality in CS patients. First, the NPAR was analyzed as a continuous variable using restricted cubic spline Cox regression models. Second, X-tile analysis was used to calculate the optimal cut-off values for the NPAR and divide the cohort into three NPAR groups. Moreover, multivariable Cox regression analyses were used to assess the association of the NPAR groups with mortality.

resultsA total of 891 patients hospitalized with CS were enrolled in this study. A nonlinear relationship between the NPAR and in-hospital and 30-day mortality was observed (all

conclusionsAdmission NPAR was independently associated with in-hospital, 30-day, and 365-day mortality in critically ill patients with CS.

Indexed as

AgedAlbuminsArea Under CurveCohort StudiesFemaleHospital MortalityHumansKaplan-Meier EstimateMaleNeutrophilsPatient AdmissionShock, CardiogenicSurvival AnalysisTreatment OutcomeAlbumins

Identifiers

PMID33294452
PMCPMC7714577

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.