Evidence map›Paper›PMID 33294449›Full record

ArticleBioMed research international2020

Differences in Clinical Features and Laboratory Results between Adults and Children with SARS-CoV-2 Infection.

Xiaoli Li, Yan Rong, Peiyan Zhang, Junli Wang, Liping Qie, Lei Rong, Jian Xu

Open access · hybridAbstract readComparative Study
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Asymptomatic SARS-CoV-2 infection: A systematic review and meta-analysis.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Pooled it
  3. Article
  4. Article
  5. Several laboratory variables indicate severity and prognosis of COVID-19.The Journal of international medical research · 2024
    Article
  6. Article
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xiaoli LiDepartment of Respiratory and Critical Care Medicine, Shenzhen Hospital, Southern Medical University, Shenzhen 518101, China.ORCID https://orcid.org/0000-0002-1004-7326
Yan RongDepartment of Respiratory and Critical Care Medicine, Shenzhen Hospital, Southern Medical University, Shenzhen 518101, China.ORCID https://orcid.org/0000-0003-0191-857X
Peiyan ZhangDepartment of Infectious Diseases, Shenzhen Third People's Hospital, Second Hospital Affiliated to Southern University of Science and Technology, Shenzhen 518000, China.ORCID https://orcid.org/0000-0002-7788-0515
Junli WangDepartment of Respiratory and Critical Care Medicine, Shenzhen Hospital, Southern Medical University, Shenzhen 518101, China.ORCID https://orcid.org/0000-0001-6862-1944
Liping QieDepartment of Pediatrics, Shenzhen Hospital, Southern Medical University, Shenzhen 518101, China.ORCID https://orcid.org/0000-0002-1397-7756
Lei RongDepartment of Respiratory and Critical Care Medicine, Shenzhen Hospital, Southern Medical University, Shenzhen 518101, China.ORCID https://orcid.org/0000-0001-9260-5012
Jian XuDepartment of Respiratory and Critical Care Medicine, Shenzhen Hospital, Southern Medical University, Shenzhen 518101, China.ORCID https://orcid.org/0000-0002-5014-2950
Southern Medical University Shenzhen Hospital · CNSouthern University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children accounts for a small proportion of all infections and is usually mild or asymptomatic. There are few studies on the clinical characteristics of SARS-CoV-2 infection in children, and the causes of the low prevalence in children remain unclear. Herein, we compared the epidemiological and clinical characteristics of SARS-CoV-2 infection between adults and children. Fifty-two patients with Coronavirus Disease 2019 (COVID-19) were retrospectively analyzed, including 38 adults and 14 children. Their clinical information such as epidemiological exposure history, laboratory indicators, chest computed tomography (CT) performance, and number of SARS-CoV-2 positive days were analyzed and compared. In children, 5 (35.71%) had mild COVID-19 and 9 (64.29%) had common type, while, in adults, 9 (23.68%) cases were mild, and 29 (76.32%) were common COVID-19. Among them, family clustering infection accounted for 50% (7/14) of child cases and 23.68% (9/36) of adult cases. Epidemiological exposure history, clinical classification, clinical symptoms, chest CT manifestations, and number of SARS-CoV-2-positive days were not significantly different between children and adults. However, the percentage of neutrophils in adults was significantly higher than that in children (

Indexed as

COVID-19Tomography, X-Ray ComputedAdolescentAdultAgedAlanine TransaminaseAspartate AminotransferasesBlood PlateletsChildChild, PreschoolFemaleHumansInfantInfant, NewbornLeukocyte CountMaleAlanine TransaminaseAspartate Aminotransferases

Identifiers

PMID33294449
PMCPMC7712632
OpenAlexW3106544123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.