ArticleRestorative dentistry & endodontics2020
Physicochemical properties, cytotoxicity and penetration into dentinal tubules of sodium hypochlorite with and without surfactants.
Article in Restorative dentistry & endodontics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Antimicrobial Efficacy of Chitosan vs. Sodium Hypochlorite AgainstMedicina (Kaunas, Lithuania) · 2026Pooled it
- Nanobubbles enhance the effects of low-concentration sodium hypochlorite on root canal irrigation.Clinical oral investigations · 2026Article
- Single- or two-visits endodontic treatment: Impact of irrigants on surface roughness, microhardness, topography, and fracture resistance of root dentin.European journal of oral sciences · 2026Article
- Effects of penetration enhancers on the performance of irrigants for root canal disinfection.Clinical oral investigations · 2025Article
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- Sonic-assisted antibacterial photodynamic therapy: a strategy for enhancing lateral canal disinfection.BMC oral health · 2024Article
- Advances in the Role of Sodium Hypochlorite Irrigant in Chemical Preparation of Root Canal Treatment.BioMed research international · 2023Review
- Mesoporous Calcium-Silicate Nanoparticles Loaded with Prussian Blue Promotes Enterococcus Faecalis Ferroptosis-Like Death by Regulating Bacterial Redox Pathway ROS/GSH.International journal of nanomedicine · 2022Article
- Physicochemical properties and penetration into dentinal tubules of calcium hypochlorite with surfactants.Brazilian dental journalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of this study was to assess the physicochemical properties, cytotoxicity and penetration into dentinal tubules of ChlorCid™ Surf (3% sodium hypochlorite [NaOCl] with surfactant) in comparison to ChlorCid™ (3% NaOCl without surfactant). MATERIALS AND
methodsThe physicochemical properties evaluated were pH, surface tension, free available chlorine (FAC) and contact angle. Cytotoxicity was evaluated in L929 fibroblasts exposed to the solutions by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide and neutral red assays. Assessment of penetration into dentinal tubules was performed by staining single-rooted permanent human teeth with crystal violet (
resultsChlorCid™ Surf and ChlorCid™ FAC values were close to those indicated by the manufacturer. ChlorCid™ Surf showed lower surface tension and contact angle on dentin, and higher pH than ChlorCid™ (
conclusionsChlorCid™ Surf showed lower surface tension, lower contact angle on root canal dentin, higher penetration into dentinal tubules and more alkaline pH, compared with ChlorCid™. However, both solutions showed similar cytotoxicity and FAC content.
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Registered trials
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