Evidence map›Paper›PMID 33294386›Full record

ArticleToxicology reports2020

Insights into the ameliorative effect of oleic acid in rejuvenating phenylhydrazine induced oxidative stress mediated morpho-functionally dismantled erythrocytes.

Adrita Banerjee, Tiyasa Dey, Arnab Kumar Ghosh, Sanatan Mishra, Debasish Bandyopadhyay, Aindrila Chattopadhyay

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Adrita BanerjeeDepartment of Physiology, Vidyasagar College, 39, Sankar Ghosh Lane, Kolkata- 700006, India.
Tiyasa DeyOxidative Stress and Free Radical Biology Laboratory, Department of Physiology, University of Calcutta, 92, APC Road, Kolkata- 700009, India.
Arnab Kumar GhoshOxidative Stress and Free Radical Biology Laboratory, Department of Physiology, University of Calcutta, 92, APC Road, Kolkata- 700009, India.
Sanatan MishraDepartment of Physiology, Vidyasagar College, 39, Sankar Ghosh Lane, Kolkata- 700006, India.
Debasish BandyopadhyayOxidative Stress and Free Radical Biology Laboratory, Department of Physiology, University of Calcutta, 92, APC Road, Kolkata- 700009, India.
Aindrila ChattopadhyayDepartment of Physiology, Vidyasagar College, 39, Sankar Ghosh Lane, Kolkata- 700006, India.
University of Calcutta · INVidyasagar University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phenylhydrazine (PHZ), an intermediate in the synthesis of fine chemicals is toxic for human health and environment. Despite of having severe detrimental effects on different physiological systems, exposure of erythrocytes to PHZ cause destruction of haemoglobin and membrane proteins leading to iron release and complete haemolysis of red blood cells (RBC). Involvement of oxidative stress behind such action triggers the urge for searching a potent antioxidant. The benefits of consuming olive oil is attributed to its 75% oleic acid (OA) content in average. Olive oil is the basic component of Mediterranean diet. Hence, OA has been chosen in our present

Indexed as

AFM, Atomic force microscopeANOVA, One way analysis of varianceATP, Adenosine triphosphateDCF, 2′ 7′-DichlorofluorescinDCFDA, 2′ 7′-Dichlorofluorescin diacetateDMSO, Dimethyl sulfoxideDTNB, 5 5′- dithio-bis-[2-nitro benzoic acid]EDTA, Ethylenediaminetetraacetic acidErythrocytesFACS, Fluorescence activated cell sorterFITC, Fluorescein isothiocyanateFSC, Forward scatteringG6PDH, Glucose 6 phosphate dehydrogenaseGPx, Glutathione PeroxidaseGR, Glutathione ReductaseGST, Glutathione-S-transferaseHb, HaemoglobinHK, HexokinaseLDH, Lactate dehydrogenaseLPO, Lipid peroxidationMDA, MalondialdehydeMorphologyMSA, Methanesulfinic acidNADPH, Reduced nicotinamide adenine di-nucleotide phosphateNBT, Nitro blue tetrazolium chlorideOA, Oleic acidOleic acidPBS, Phosphate buffered salinePFK, PhosphofructokinasePhenylhydrazinePHZ, PhenylhydrazinePPP, Pentose Phosphate PathwayRBC, Red blood CellROSROS, Reactive oxygen speciesSOD, Superoxide dismutaseTBARS, Thiobarbituric acid reactive substanceTBA, Thiobarbituric acidTCA, Tricholoroacetic acidToxicity

Identifiers

PMID33294386
PMCPMC7689048
OpenAlexW3099001394

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.