Evidence map›Paper›PMID 33294273›Full record

ArticleAmerican journal of cancer research2020

A multi-class scoring system based on CT features for preoperative prediction in gastric gastrointestinal stromal tumors.

Jianxia Xu, Jiaping Zhou, Xiaojie Wang, Shufeng Fan, Xiaoshan Huang, Xingwu Xie, Risheng Yu

Open access · greenAbstract read
In one paragraph

Article in American journal of cancer research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Jianxia XuDepartment of Radiology, The Second Affiliated Hospital of Zhejiang Chinese Medical University 318 Chaowang Road, Hangzhou 310005, Zhejiang Province, China.
Jiaping ZhouDepartment of Radiology, Second Affiliated Hospital, School of Medicine, Zhejiang University 88 Jiefang Road, Hangzhou 310009, Zhejiang Province, China.
Xiaojie WangDepartment of Radiology, Second Affiliated Hospital, School of Medicine, Zhejiang University 88 Jiefang Road, Hangzhou 310009, Zhejiang Province, China.
Shufeng FanDepartment of Radiology, The Second Affiliated Hospital of Zhejiang Chinese Medical University 318 Chaowang Road, Hangzhou 310005, Zhejiang Province, China.
Xiaoshan HuangDepartment of Radiology, The Second Affiliated Hospital of Zhejiang Chinese Medical University 318 Chaowang Road, Hangzhou 310005, Zhejiang Province, China.
Xingwu XieDepartment of Radiology, Renmin Hospital, Hubei University of Medicine Shiyan 442000, Hubei Province, China.
Risheng YuDepartment of Radiology, Second Affiliated Hospital, School of Medicine, Zhejiang University 88 Jiefang Road, Hangzhou 310009, Zhejiang Province, China.
Second Affiliated Hospital of Zhejiang University · CNZhejiang Chinese Medical University · CNHubei University of Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our study aimed to establish and validate a multi-class scoring system for preoperative gastric gastrointestinal stromal tumors (GISTs) risk stratifications based on CT features. 150 gastric GIST patients who underwent contrast-enhanced CT examination and surgical resection from hospital 1 were retrospectively analyzed as the training cohort, and 61 patients from hospitals 2 and 3 were included as the validation cohort. A model was established by logistic regression analysis and weighted to be a scoring model. A calibration test, area under the receiver operating characteristic (ROC) curve (AUC), and cutoff points were determined for the score model. The model was also divided into three score ranges for convenient clinical evaluation. Five CT features were included in the score model, including tumor size (4 points), ill-defined margin (6 points), intratumoral enlarged vessels (5 points), heterogeneous enhancement pattern (4 points), and exophytic or mixed growth pattern (2 points). Then, based on the calibration results, performance was merely assessed as very low and high* risk. The AUCs of the score model for very low risk and high* risk were 0.973 and 0.977, and the cutoff points were 3 points (97.30%, 93.81%) and 7 points (92.19%, 94.19%), respectively. In the validation cohort, the AUCs were 0.912 and 0.972, and the cutoff values were 3 points (92.31%, 85.42%) and 5 points (100%, 87.88%), respectively. The model was stratified into 3 ranges: 0-3 points for very low risk, 4-8 points for low risk, and 9-21 points for high* risk. A concise and practical score system for gastric GISTs risk stratification was proposed.

Indexed as

computed tomographyGastrointestinal stromal tumorspreoperativerisk classificationscoring system

Identifiers

PMID33294273
PMCPMC7716157
OpenAlexW3110744916

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.