Evidence map›Paper›PMID 33294260›Full record

ArticleAmerican journal of cancer research2020

Chiauranib selectively inhibits colorectal cancer with

Haofan Yin, Jinye Xie, Ping Jiang, Xi Jiang, Deyu Duan, Junhua Qi, Zhaofan Luo, Caiqi Ma, Honghai Hong

Open access · greenAbstract read
In one paragraph

Article in American journal of cancer research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Haofan YinDepartment of Clinical Laboratory, The Seventh Affiliated Hospital of Sun Yat-sen University Shenzhen, Guangdong, China.
Jinye XieDepartment of Laboratory Medicine, Zhongshan People's Hospital Zhongshan, Guangdong, China.
Ping JiangDepartment of Clinical Medical Laboratory, Guangzhou First' People Hospital, School of Medicine, South China University of Technology Guangzhou, Guangdong, China.
Xi JiangDepartment of Clinical Laboratory, The Seventh Affiliated Hospital of Sun Yat-sen University Shenzhen, Guangdong, China.
Deyu DuanDepartment of Clinical Laboratory, The Seventh Affiliated Hospital of Sun Yat-sen University Shenzhen, Guangdong, China.
Junhua QiDepartment of Clinical Laboratory, The Seventh Affiliated Hospital of Sun Yat-sen University Shenzhen, Guangdong, China.
Zhaofan LuoDepartment of Clinical Laboratory, The Seventh Affiliated Hospital of Sun Yat-sen University Shenzhen, Guangdong, China.
Caiqi MaReproductive Medical Center, Guangzhou Women and Children's Medical Center of Sun Yat-sen University Guangzhou, Guangdong, China.
Honghai HongDepartment of Clinical Laboratory, The Third Affiliated Hospital of Guangzhou Medical University Guangzhou, Guangdong, China.
Sun Yat-sen University · CNGuangzhou First People's Hospital · CNGuangzhou Women and Children Medical Center · CNThird Affiliated Hospital of Guangzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is one of the top three most deadly cancers despite using chemotherapy based on oxaliplatin or irinotecan combined with targeted therapy. Chiauranib has recently been identified to be a promising anticancer candidate with impressive efficacy and safety. However, the role and molecular mechanisms of Chiauranib in the treatment of CRC remain to be elucidated. Our study shows that Chiauranib inhibits cell proliferation and induces apoptosis in

Indexed as

chiauranibColorectal cancerROS

Identifiers

PMID33294260
PMCPMC7716162
OpenAlexW3111360083

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.