Evidence map›Paper›PMID 33294223›Full record

ArticleTuberculosis research and treatment2020

Ion Transport Modulators as Antimycobacterial Agents.

Steven C Mitini-Nkhoma, Narmada Fernando, G K D Ishaka, Shiroma M Handunnetti, Sisira L Pathirana

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Tuberculosis research and treatment, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Host-directed therapy for tuberculosis.European journal of medical research · 2025
    Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Steven C Mitini-NkhomaInstitute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, No: 90, Cumaratunga Munidasa Mawatha, Colombo 3, Sri Lanka.ORCID https://orcid.org/0000-0002-3276-6890
Narmada FernandoInstitute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, No: 90, Cumaratunga Munidasa Mawatha, Colombo 3, Sri Lanka.
G K D IshakaInstitute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, No: 90, Cumaratunga Munidasa Mawatha, Colombo 3, Sri Lanka.
Shiroma M HandunnettiInstitute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, No: 90, Cumaratunga Munidasa Mawatha, Colombo 3, Sri Lanka.ORCID https://orcid.org/0000-0002-0051-7232
Sisira L PathiranaInstitute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, No: 90, Cumaratunga Munidasa Mawatha, Colombo 3, Sri Lanka.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is an urgent need for better and safer therapeutic interventions for tuberculosis (TB). We assessed the effects of FDA-approved ion transport modulators, namely, ambroxol HCl, amiloride HCl, diazoxide, digoxin, furosemide, hydrochlorothiazide (HCTZ), metformin, omeprazole, pantoprazole, phenytoin, verapamil, and drug X and Y on the growth of free and intracellular

Identifiers

PMID33294223
PMCPMC7700046

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.