Evidence map›Paper›PMID 33294015›Full record

ArticleEvolutionary applications2020

Extent of polymorphism and selection pressure on the

Audrey Arnal, Liliana Villanueva-Lizama, Christian Teh-Poot, Claudia Herrera, Eric Dumonteil

Abstract read
In one paragraph

Article in Evolutionary applications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Vaccines against chronicExpert review of vaccines · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Fighting Strategies Against Chagas' Disease: A Review.Pathogens (Basel, Switzerland) · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. The Low Variability of Tc24 inPathogens (Basel, Switzerland) · 2023
    Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. AssessingPathogens (Basel, Switzerland) · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Audrey ArnalLaboratorio de Parasitología Centro de Investigaciones Regionales "Dr Hideyo Noguchi" Universidad Autónoma de Yucatán Mérida Mexico.
Liliana Villanueva-LizamaLaboratorio de Parasitología Centro de Investigaciones Regionales "Dr Hideyo Noguchi" Universidad Autónoma de Yucatán Mérida Mexico.
Christian Teh-PootLaboratorio de Parasitología Centro de Investigaciones Regionales "Dr Hideyo Noguchi" Universidad Autónoma de Yucatán Mérida Mexico.
Claudia HerreraDepartment of Tropical Medicine School of Public Health and Tropical Medicine Tulane University New Orleans LA USA.
Eric DumonteilDepartment of Tropical Medicine School of Public Health and Tropical Medicine Tulane University New Orleans LA USA.ORCID https://orcid.org/0000-0001-9376-0209

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionChagas disease, caused by the protozoan parasite METHODS AND

resultsWe quantified its level of polymorphism within and between DISCUSSION: Together, these results show that a vaccine based on Tc24 is likely to be effective against a wide diversity of parasite strains across the American continent, and further development of this vaccine candidate should be a high priority.

Indexed as

antigenic variationcalcium‐bindingChagas diseasekinetoplastidvaccine

Identifiers

PMID33294015
PMCPMC7691455

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.