ArticleJournal of exercise science and fitness2021
Effect of blood flow restriction during low-intensity resistance training on bone markers and physical functions in postmenopausal women.
Article in Journal of exercise science and fitness, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 7 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Systematic review and meta-analysis of the effects of blood flow restriction training on bone health in older adults.Scientific reports · 2025Pooled it
- Effects of exercise on bone metabolism in postmenopausal women: a systematic review and meta-analysis of randomized controlled trials.Frontiers in endocrinology · 2025Pooled it
- Effect of Blood Flow Restriction on Gait and Mobility in Older Adults: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2024Pooled it
- Effect of blood flow restriction training on health promotion in middle-aged and elderly women: a systematic review and meta-analysis.Frontiers in physiology · 2024Pooled it
- Effects of upper extremity blood flow restriction training on muscle strength and hypertrophy: a systematic review and meta-analysis.Frontiers in physiology · 2024Pooled it
- The Effect of Low Intensity Resistance Training with Blood Flow Restriction on Fall Resistance in Middle-Aged and Older Adults: A Meta-Analysis.International journal of environmental research and public health · 2023Pooled it
- Effects of blood flow restriction training on bone metabolism: a systematic review and meta-analysis.Frontiers in physiology · 2023Pooled it
- Cardiovascular Responses to a Full Resistance Training Session Performed with and Without Blood Flow Restriction.Sports (Basel, Switzerland) · 2025Article
- Blood flow restriction training in microgravity: a review of multisystem physiological benefits and implementation challenges for long-duration space missions.NPJ microgravity · 2025Review
- Idiosyncratic bone responses to blood flow restriction exercise: new insights and future directions.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Review
- The effects of blood flow restriction training on post activation potentiation and upper limb muscle activation: a meta-analysis.Frontiers in physiology · 2024Review
- Physical fitness and blood parameters outcomes of breast cancer survivor in a low-intensity circuit resistance exercise program.Open medicine (Warsaw, Poland) · 2024Article
- Blood Flow Restriction in Oncological Patients: Advantages and Safety Considerations.Healthcare (Basel, Switzerland) · 2023Review
- Knee Loading With Blood Flow Restriction Can Enhance Recovery After Total Knee Arthroplasty.Cureus · 2023Review
- Blood Flow Restricted Cycling Impairs Subsequent Jumping But Not Balance Performance Slightly More Than Non-Restricted Cycling: An Acute Randomized Controlled Cross-Over Trial.Journal of sports science & medicine · 2023Article
- Effectiveness of Blood Flow Restriction in Neurological Disorders: A Systematic Review.Healthcare (Basel, Switzerland) · 2022Review
- Acute effects of the resistance exercise associated with different blood flow restriction pressures on bone remodeling biomarkers.Journal of exercise science and fitness · 2022Article
- Acute and Chronic Bone Marker and Endocrine Responses to Resistance Exercise With and Without Blood Flow Restriction in Young Men.Frontiers in physiology · 2022Article
- Blood Flow Restriction: Cause for Optimism, But Let's Not Abandon The Fundamentals.International journal of sports physical therapy · 2021Article
- Molecular Regulation of Skeletal Muscle Growth and Organelle Biosynthesis: Practical Recommendations for Exercise Training.International journal of molecular sciences · 2021Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to investigate the effects of 12-week low intensity resistance training (RT) with blood flow restriction on bone mineral density (BMD), bone turnover markers (BTM), physical functions, and blood lactate concentration in postmenopausal women with osteoporosis or osteopenia.
methods26 study participants (56 ± 1.8yrs, T-score: -2.5 ± 0.7) were randomly assigned into Moderate to High-Intensity RT (MHIRT, n = 7), BFR combined with Low-Intensity RT (LIBFR, n = 7), Low-Intensity RT (LIRT, n = 6), or Control group (CON, n = 6). Exercise group performed leg press, leg extension, biceps curl, and triceps extension 3 times a week for 12 weeks. Training intensity were set at 60% of 1-repetition maximum (1-RM) for MHIRT, and at 30% of 1-RM for LIBFR and LIRT, and reset every 4 weeks for increasing intensity.
resultsLower, and upper limb 1-RM only increased in MHIRT (65%, p < 0.001), and LIBFR (40%, p < 0.05), while LIRT only showed increment on lower limb 1-RM (28%, p < 0.05). All exercise groups demonstrated significant increment on blood lactate concentration after training session (p < 0.001). However, LIBFR showed 2.7 folds higher increment than LIRT (p < 0.001). Although no changes were observed in MHIRT, LIBFR, and LIRT, CON showed significant decrease in BMD (p < 0.05). While, LIRT showed no responses on BTM, LIBFR significantly increased bone formation markers (P1NP) about 7.05 ng/ml (p < 0.05). Lastly, balance improvement was only found in MHIRT, and LIBFR (p < 0.05).
conclusion12-week LIBFR can be implied as a safe, and effective method to improve muscle strength, P1NP, and balance similar to MHIRT in postmenopausal women with osteoporosis or osteopenia.
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