Evidence map›Paper›PMID 33293954›Full record

ArticleInternational journal of endocrinology2020

Serum Kisspeptin and AMH Levels Are Good References for Precocious Puberty Progression.

Jiang Xue, Wei Song, Min Si, Chao Sun, Kailin Li, Wei Wang, Shuang Liang, Yanfeng Xiao

Open access · goldAbstract read
In one paragraph

Article in International journal of endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jiang Xue *Department of Pediatrics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Wei Song *Department of Pediatrics, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.ORCID https://orcid.org/0000-0003-0988-1097
Min SiDepartment of Intensive Care Unit, Jinan Central Hospital Affiliated to Shandong First Medical University, Jinan, China.
Chao SunDepartment of Central Laboratory, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Kailin LiDepartment of Central Laboratory, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.ORCID https://orcid.org/0000-0003-1753-3105
Wei WangDepartment of Interventional Medicine, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.ORCID https://orcid.org/0000-0002-2124-5328
Shuang LiangDepartment of Pediatrics, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.ORCID https://orcid.org/0000-0001-9067-6829
Yanfeng XiaoDepartment of Pediatrics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.ORCID https://orcid.org/0000-0001-6803-1792
Second Hospital of Shandong University · CNJinan Central Hospital · CNSecond Affiliated Hospital of Xi'an Jiaotong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe aim of this study was to evaluate the levels of kisspeptin and AMH in children with PT or CPP or controls to provide a reference for diagnosis and prognosis.

methods38 Chinese children with central precocious puberty (CPP), 38 Chinese children with premature thelarche (PT), and 75 controls were recruited.

resultsIn CPP girls, AMH levels decreased significantly compared to control girls at T2 stage. Compared with the PT and control groups, AMH is the lowest in girls in the CPP group at T3 stage. Kisspeptin decreased significantly in girls in the PT group and increased significantly in girls in the control group from T2 stage to T3 stage. At T3 stage, kisspeptin was significantly higher in girls in the CPP and control groups than in the PT group. In the control group, kisspeptin was significantly higher in boys than in girls at T2 stage. AMH and height were negatively correlated in the girls group.

conclusionsKisspeptin and AMH have a unique significance in the auxiliary diagnosis, the differential diagnosis, the treatment, and prognosis of sexual puberty disorder.

Identifiers

PMID33293954
PMCPMC7700058
OpenAlexW3107892864

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.