ArticleClinical epidemiology2020
The Risk of Selection Bias in a Clinical Multi-Center Cohort Study. Results from the Norwegian Cognitive Impairment After Stroke (Nor-COAST) Study.
Article in Clinical epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 44 citations in OpenAlex.
- Associations between systemic inflammation and cognitive trajectories post-stroke.Scientific reports · 2025Observational
- The Longitudinal Course of Physical Activity Behavior Poststroke and Its Variation Across Subgroups: The Norwegian Cognitive Impairment After Stroke Study.Physical therapy · 2025Observational
- Deep learning classification integrating embryo images with associated clinical information from ART cycles.Scientific reports · 2025Article
- Impact of Insufficient or Excessive Sleep Duration on Cognitive Function After Stroke: The Norwegian Cognitive Impairment After Stroke Study.Journal of the American Heart Association · 2025Article
- Impact of a stroke care pathway on self-perceived health 3 months after stroke.Journal of rehabilitation medicine · 2025Article
- Follow-Up in Primary Care After Ischemic Stroke - Insights From the Nor-COAST Study.International journal of general medicine · 2025Article
- Diagnostic accuracy of the Clock Drawing Test in screening for early post-stroke neurocognitive disorder: the Nor-COAST study.BMC neurology · 2024Article
- Reduced physical activity level was associated with poorer quality of life during the early phase of the COVID-19 pandemic: a sub-study of the last-long trial.Journal of rehabilitation medicine · 2023Article
- Physical Activity Behavior and Its Association With Global Cognitive Function Three Months After Stroke: The Nor-COAST Study†.Physical therapy · 2023Article
- Article
- Plasma Inflammatory Biomarkers Are Associated With Poststroke Cognitive Impairment: The Nor-COAST Study.Stroke · 2023Observational
- The relationship of acute delirium with cognitive and psychiatric symptoms after stroke: a longitudinal study.BMC neurology · 2022Article
- Use of lipid-lowering therapy after ischaemic stroke and expected benefit from intensification of treatment.Open heart · 2022Article
- Is Frailty Index a better predictor than pre-stroke modified Rankin Scale for neurocognitive outcomes 3-months post-stroke?BMC geriatrics · 2022Article
- Longitudinal Brain Changes After Stroke and the Association With Cognitive Decline.Frontiers in neurology · 2022Article
- Resilience and Its Association With Activities of Daily Living 3 Months After Stroke.Frontiers in neurology · 2022Article
- Neuroimaging markers of dual impairment in cognition and physical performance following stroke: The Nor-COAST study.Frontiers in aging neuroscience · 2022Article
- Article
- Investigating novel biomarkers of immune activation and modulation in the context of sedentary behaviour: a multicentre prospective ischemic stroke cohort study.BMC neurology · 2021Article
- Pre-stroke cognitive impairment is associated with vascular imaging pathology: a prospective observational study.BMC geriatrics · 2021Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe Norwegian Cognitive Impairment After Stroke (Nor-COAST) study aimed to estimate the prevalence and incidence of neurocognitive disorder in an unselected stroke cohort. The aim of the present study was to investigate whether selection bias occurred by comparing baseline characteristics from participants with non-participants in Nor-COAST. PATIENTS AND
methodsNor-COAST is a prospective cohort multi-center study, recruiting participants from five Norwegian hospitals. Patients with the diagnosis of acute stroke were screened for inclusion. Baseline data from the participants recruited between May 2015 and March 2017 were compared to corresponding data from those not participating in Nor-COAST but registered in the Norwegian Stroke Registry. Regression analysis was used to assess whether age, stroke severity, sex and stroke subtype were independently associated with inclusion in the study.
resultsOut of 2505 available patients, 815 (32.5%) were included in Nor-COAST. There were no differences between participants and non-participants with respect to age (mean (SD) age 73.5 (11.7) versus 74.2 (14.5) years) or sex (44.8% versus 46.9% women). A significantly larger proportion of the participants were independent prior to stroke (87% versus 78%), had mild strokes (69% versus 55%) and suffered from cerebral infarction (90% versus 84%). The regression analysis showed decreased odds ratio (OR) of being included for those with higher degree of pre-stroke dependency (OR 0.895, 95% CI 0.825 to 0.971, p=0.007) and a more severe stroke (OR 0.952, 95% CI 0.939 to 0.966, p<0.001).
conclusionThe participants in Nor-COAST had a better pre-stroke health condition and milder strokes compared to non-participants. However, the participants should be regarded as representative of the majority of the stroke population which suffers from mild strokes. Nevertheless, baseline information for non-participants should be available also in future clinical studies to make it easier to identify which part of the stroke population the results can be generalized to.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.