ArticleScientific reports2020
Value of peak strain dispersion in discovering left ventricular dysfunction in diabetes mellitus.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed, 17 citations in OpenAlex.
- Left Atrial Volume and Phasic Function Assessed by 4D Auto LAQ Echocardiography in Treatment-Naive, Newly Diagnosed Type 2 Diabetes Mellitus Patients Without Hypertension or Obesity.Journal of cardiovascular development and disease · 2026Article
- Left ventricular myocardial work in pregnant women with autoimmune diseases.Frontiers in cardiovascular medicine · 2026Article
- Albuminuria is independently associated with preclinical left ventricular systolic dysfunction: The TESEO study.World journal of diabetes · 2025Article
- Myocardial work parameters in left bundle branch area pacing versus other pacing techniques: a systematic review and aggregate comparative analysis.International journal of cardiology. Heart & vasculature · 2025Review
- Echocardiographic imaging in patients with conduction system pacing.Cardiovascular ultrasound · 2025Review
- Myocardial Work Indices in Patients Recently Recovered from Mild-to-Moderate COVID-19.Journal of clinical medicine · 2024Article
- Subclinical impairment of left ventricular myocardium function in type 2 diabetes mellitus patients with or without hypertension.World journal of diabetes · 2024Article
- Evaluation of left ventricular systolic function in type 2 diabetes mellitus patients with and without peripheral vascular disease.World journal of diabetes · 2024Article
- Interrelationships between Peak Strain Dispersion, Myocardial Work Indices, Isovolumetric Relaxation and Systolic-Diastolic Coupling in Middle-Aged Healthy Subjects.Journal of clinical medicine · 2023Article
- Hemodynamic Effects of Permanent His Bundle Pacing Compared to Right Ventricular Pacing Assessed by Two-Dimensional Speckle-Tracking Echocardiography.International journal of environmental research and public health · 2021Article
- Evaluation of left ventricular systolic synchrony by peak strain dispersion in patients with rheumatoid arthritis.The Journal of international medical research · 2021Article
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Authors and funding
5 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Cardiovascular disease is one of the main causes of death in diabetes mellitus (DM) patients. The aim of the current study was to explore the value of peak strain dispersion (PSD) for discovering early-stage left ventricular (LV) dysfunction in type 2 diabetes mellitus (T2DM) patients. One hundred and one T2DM patients and sixty healthy subjects were selected for this study. T2DM patients were further divided into controlled blood glucose (HbA1c < 7%, n = 46) and uncontrolled blood glucose (HbA1c ≥ 7%, n = 55) subgroups. All participants underwent conventional echocardiography and two-dimensional speckle-tracking echocardiography. Our results showed that an obvious difference was not observed in global longitudinal strain (GLS) between the controlled blood glucose group and the control group (- 20.34% vs - 21.22%, P = 0.068). Compared with the healthy controls, the uncontrolled blood glucose group showed an impaired GLS (- 18.62% vs - 21.22%, P < 0.001). Nevertheless, PSD was appreciably increased in the controlled blood glucose group (36.02 ms vs 32.48 ms, P = 0.01) and uncontrolled blood glucose group (57.51 ms vs 32.48 ms, P < 0.001). Multivariate linear regression analysis showed that HbA1c was closely related to PSD lesion in the LV in the T2DM group (β = 0.520, P < 0.001). PSD plays an important role in evaluating the coordination and synchronization of myocardial movement and provides a more accurate and sensitive index assessment of early LV systolic function in T2DM patients. In addition, HbA1c levels were related to LV dysfunction.
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