Evidence map›Paper›PMID 33293655›Full record

ArticleScientific reports2020

Incidence of malignancy and related mortality after kidney transplantation: a nationwide, population-based cohort study in Korea.

Seri Jeong, Ho Sup Lee, Seom Gim Kong, Da Jung Kim, Sangjin Lee, Min-Jeong Park, Wonkeun Song, John Hoon Rim, Hyung Jik Kim

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.

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  17. Incidence ofTransplant international : official journal of the European Society for Organ Transplantation · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Seri JeongDepartment of Laboratory Medicine, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, 07441, South Korea.
Ho Sup LeeDepartment of Hematology-Oncology, Kosin University College of Medicine, Busan, 49267, South Korea.
Seom Gim KongDepartment of Pediatrics, Kosin University College of Medicine, Busan, 49267, South Korea.
Da Jung KimDepartment of Hematology-Oncology, Kosin University College of Medicine, Busan, 49267, South Korea.
Sangjin LeeDepartment of Statistics, Graduate School, Pusan National University, Busan, 46241, South Korea.
Min-Jeong ParkDepartment of Laboratory Medicine, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, 07441, South Korea.
Wonkeun SongDepartment of Laboratory Medicine, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, 07441, South Korea.
John Hoon RimDepartment of Pharmacology, Yonsei University College of Medicine, Seoul, 03722, South Korea.
Hyung Jik KimDepartment of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, 22, Gwanpyeong-ro 170 beon-gil, Dongan-gu, 14068, Anyang-si, Gyeonggi-do, South Korea. hyung@hallym.or.kr.
Hallym University Kangnam Sacred Heart Hospital · KRKosin University · KRHallym University · KRPusan National University · KRYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-transplant malignancy (PTM) is a leading cause of premature mortality among kidney transplantation recipients. However, population-based cohort studies that cover incidence, mortality, and risk factors for PTM are rarely reported, especially in East Asia. We designed a retrospective cohort study using a national population-based database. A total of 9915 kidney recipients between 2003 and 2016 were included. During this period, 598 cases (6.0%) of de novo PTM occurred. The most common PTM was thyroid cancer (14.2%), followed by colorectal (11.2%), kidney (10.7%), and stomach cancers (8.9%). The standardised incidence ratio for all-site cancer was 3.9. The risks of Kaposi sarcoma (192.9) and kidney cancer (21.1) were more than 10 times those of the general population. Cancer-related deaths were 89 (14.9%) with liver cancer being the highest (14.6%), followed by lung cancer (13.5%), non-Hodgkin lymphoma (NHL) (12.4%), stomach cancer (9.0%), and colorectal cancer (7.9%). The standardised mortality ratio (SMR) was slightly elevated (1.4). A notable increase in SMR was observed for lymphoma (9.3 for Hodgkin lymphoma and 5.5 for NHL). Older age and graft failure were significantly related to PTM. These findings reflecting geographical variation have implications for the development of strategies for fatal cancers to prevent premature deaths from PTM.

Indexed as

AdultAge FactorsColorectal NeoplasmsFemaleHumansIncidenceKidney TransplantationLiver NeoplasmsLung NeoplasmsLymphoma, Non-HodgkinMaleMiddle AgedMortalityNeoplasmsRepublic of KoreaRetrospective Studies

Identifiers

PMID33293655
PMCPMC7722878
OpenAlexW3112758512

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.