Evidence map›Paper›PMID 33293642›Full record

ArticleScientific reports2020

Radiosurgery for unruptured brain arteriovenous malformations in the pre-ARUBA era: long-term obliteration rate, risk of hemorrhage and functional outcomes.

Iulia Peciu-Florianu, Henri-Arthur Leroy, Elodie Drumez, Chloé Dumot, Rabih Aboukaïs, Gustavo Touzet, Xavier Leclerc, Serge Blond, Jean-Paul Lejeune, Nicolas Reyns

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Iulia Peciu-FlorianuDepartment of Neurosurgery, Univ.Lille, CHU Lille, 59000, Lille, France.
Henri-Arthur LeroyDepartment of Neurosurgery, Univ.Lille, CHU Lille, 59000, Lille, France. henriarthurleroy@gmail.com.
Elodie DrumezULR 2694 - METRICS: Évaluation des Technologies de Santé et des Pratiques Médicales, Univ. Lille, CHU Lille, 59000, Lille, France.
Chloé DumotDepartment of Neurosurgery, Univ.Lille, CHU Lille, 59000, Lille, France.
Rabih AboukaïsDepartment of Neurosurgery, Univ.Lille, CHU Lille, 59000, Lille, France.
Gustavo TouzetDepartment of Neurosurgery, Univ.Lille, CHU Lille, 59000, Lille, France.
Xavier LeclercDepartment of Neuroradiology, Univ. Lille, CHU Lille, 59000, Lille, France.
Serge BlondDepartment of Neurosurgery, Univ.Lille, CHU Lille, 59000, Lille, France.
Jean-Paul LejeuneDepartment of Neurosurgery, Univ.Lille, CHU Lille, 59000, Lille, France.
Nicolas ReynsDepartment of Neurosurgery, Univ.Lille, CHU Lille, 59000, Lille, France.
Université de Lille · FRCentre Hospitalier Universitaire de Lille · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The management of non-hemorrhagic arteriovenous malformations (AVMs) remains a subject of debate, even more since the ARUBA trial. Here, we report the obliteration rate, the risk of hemorrhage and the functional outcomes after Gamma Knife radiosurgery (GKRS) as first-line treatment for non-hemorrhagic AVMs treated before the ARUBA publication, in a reference university center with multimodal AVM treatments available. We retrospectively analyzed data from a continuous series of 172 patients harboring unruptured AVMs treated by GKRS as first-line treatment in our Lille University Hospital, France, between April 2004 and December 2013. The primary outcome was obliteration rate. Secondary outcomes were the hemorrhage rate, the modified Rankin Scale (mRS), morbidity and epilepsy control at last follow-up. The minimal follow-up period was of 3 years. Median age at presentation was 40 years (IQR 28; 51). Median follow-up was 8.8 years (IQR 6.8; 11.3). Median target volume was 1.9 cm

Indexed as

AdultCerebral AngiographyEpilepsyFemaleFranceHemorrhageHumansIntracranial Arteriovenous MalformationsKaplan-Meier EstimateMaleMiddle AgedRadiosurgeryRetreatmentRetrospective StudiesTreatment Outcome

Identifiers

PMID33293642
PMCPMC7723058
OpenAlexW3111457733

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.