ArticleScientific reports2020
Determinants of delay in diagnosis and end stage at presentation among breast cancer patients in Iran: a multi-center study.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 5 of them syntheses that pooled it.
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Who cites it
35 citing papers in PubMed, 5 syntheses or guidelines pooled it, 61 citations in OpenAlex.
- Pooled it
- Molecular signatures of breast cancer in the Iranian population: a review of cell growth and cell cycle regulators.Journal of cancer research and clinical oncology · 2025Pooled it
- Advanced-stage breast cancer diagnosis and its determinants in Ethiopia: a systematic review and meta-analysis.BMC women's health · 2024Pooled it
- Health system barriers influencing timely breast cancer diagnosis and treatment among women in low and middle-income Asian countries: evidence from a mixed-methods systematic review.BMC health services research · 2022Pooled it
- Benefits of breast self-examinations for medically underserved populations: A systematic review.Women's health (London, England)Pooled it
- Determinants of patient delay and its association with quality of life among young women with breast cancer in China: A cross-sectional study.Asia-Pacific journal of oncology nursing · 2026Article
- SIVA1 Knockdown Drives Aggressive Phenotypes in Triple-Negative Breast Cancer Cells while Enhancing Paclitaxel Efficacy.ACS omega · 2026Article
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- The effect of the number of negative lymph nodes removed during surgery on the survival and recurrence rates of patients with breast cancer after surgery.BMC surgery · 2026Article
- Factors Associated with Delays in Breast Cancer Diagnosis in Low- and Middle-income Countries: A Scoping Review.International journal of community based nursing and midwifery · 2026Review
- Causes of diagnostic and treatment delays in locally advanced breast cancer: a nationwide multicenter survey and electronic health records analysis in Turkiye.European journal of public health · 2025Article
- Perceived barriers to timely diagnosis among Iranian women diagnosed with advanced breast cancer: a qualitative study.BMJ open · 2025Article
- How Obesity Complicates Breast Cancer Care: Insights From a Systematic Review of Case Reports.Cureus · 2025Review
- Burdens of Breast Cancer and Projections for 2030 Among Women in Asia: Findings from the 2021 Global Burden of Disease Study.Current oncology (Toronto, Ont.) · 2025Article
- An innovative approach to the multidisciplinary treatment of uninsured breast cancer patients.Cancer causes & control : CCC · 2025Article
- Evaluation of breast cancer symptoms and risk factors in women: the case of Türkiye.Revista da Escola de Enfermagem da U S P · 2025Article
- Diagnostic delay among symptomatic breast cancer patients: a study in Sudanese women.Journal of preventive medicine and hygiene · 2024Article
- Three-year survival of breast cancer patients attending a one-stop breast care clinic nested within a primary care health facility in sub-Saharan Africa-Zambia.International journal of cancer · 2024Article
- An inquiry into patient versus health system factors contribution to the diagnostic interval in oral cancer: an early diagnosis study from Kerala, India.Ecancermedicalscience · 2024Article
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Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
One of the reasons for high mortality of breast cancer (BC) is long delay in seeking medical care and end stage at presentation. This study was designed to measure the association between a wide range of socio-demographic and clinical factors with diagnostic delay in BC and stage at presentation among Iranian patients. From June 2017 to December 2019, 725 patients with newly diagnosed BC in Shiraz and Kermanshah were selected and information on BC diagnosis delay was obtained from the patient's medical record. Data on socio-economic status was obtained via a structured interview. Our findings suggest that 45.8% of the patients were diagnosed at a late stage (stage 3 or higher). A total of 244 (34%) patients had more than 3 months delay in diagnosis. We found a significant association between stage at diagnosis and place of residence (adjusted odds ratio (aOR rural vs. urban = 1.69, 95% CI 1.49-1.97), marital status (aOR 1.61, 95% CI 1.42-1.88), family history of BC (aOR 1.46, 95% CI 1.01-2.13), and history of benign breast disease (BBD) (aOR 1.94, 95% CI 1.39-2.72) or unaware of breast self-examination (BSE) (aOR 1.42, 95% CI 1.42-1.85), delay time (aOR 3.25, 95% CI 1.04-5.21), and left breast tumor (aOR right vs. left 2.64, 95% CI 1.88-3.71) and smoking (aOR no vs. yes 1.59, 95% CI 1.36-1.97). Also, delay in diagnosis was associated with age, family income, health insurance, place of residence, marital status, menopausal status, history of BBD, awareness of breast self-examination, type of first symptoms, tumor histology type, BMI and comorbidity (p < 0.05 for all). Factors including history of BBD, awareness of BSE, and suffering from chronic diseases were factors associated with both delay in diagnosis and end stage of disease. These mainly modifiable factors are associated with the progression of the disease.
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