Trial reportScientific reports2020
Non-invasive pulmonary artery pressure estimation by electrical impedance tomography in a controlled hypoxemia study in healthy subjects.
Trial report in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 26 citations in OpenAlex.
- Utility of electrical impedance tomography to measure neonatal pulmonary circulation changes: a lamb study.Pediatric research · 2026Article
- Non-invasive estimation of beat-by-beat aortic blood pressures from electrical impedance tomography data processed by machine learning.Journal of clinical monitoring and computing · 2025Article
- Electrical impedance tomography in neonates: a review.Pediatric research · 2025Review
- Novel three-dimensional electrical impedance tomography for noninvasive detection of lung perfusion.Journal of thoracic disease · 2025Article
- A nomogram model based on clinical and 3D-EIT parameters for CTEPH diagnosis.Respiratory research · 2025Article
- Remotely Powered Two-Wire Cooperative Sensors for Bioimpedance Imaging Wearables.Sensors (Basel, Switzerland) · 2024Article
- Absolute values of regional ventilation-perfusion mismatch in patients with ARDS monitored by electrical impedance tomography and the role of dead space and shunt compensation.Critical care (London, England) · 2024Article
- [Research progress on electrical impedance tomography in pulmonary perfusion].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2023Review
- Flexible Electrodes as a Measuring System of Electrical Impedance Imaging.Materials (Basel, Switzerland) · 2023Article
- Article
- Non-Invasive Hemodynamics Monitoring System Based on Electrocardiography via Deep Convolutional Autoencoder.Sensors (Basel, Switzerland) · 2021Article
- Correlation of Pulse Wave Transit Time with Pulmonary Artery Pressure in a Porcine Model of Pulmonary Hypertension.Biomedicines · 2021Article
- Lung Perfusion Assessment by Bedside Electrical Impedance Tomography in Critically Ill Patients.Frontiers in physiology · 2021Review
- Noninvasive Estimation of Right Atrial, Right Ventricular, and Pulmonary Systolic Pressure: "A Good Story Never Ends".Journal of cardiovascular echographyReview
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
Abstract
Pulmonary hypertension is a hemodynamic disorder defined by an abnormal elevation of pulmonary artery pressure (PAP). Current options for measuring PAP are limited in clinical practice. The aim of this study was to evaluate if electrical impedance tomography (EIT), a radiation-free and non-invasive monitoring technique, can be used for the continuous, unsupervised and safe monitoring of PAP. In 30 healthy volunteers we induced gradual increases in systolic PAP (SPAP) by exposure to normobaric hypoxemia. At various stages of the protocol, the SPAP of the subjects was estimated by transthoracic echocardiography. In parallel, in the pulmonary vasculature, pulse wave velocity was estimated by EIT and calibrated to pressure units. Within-cohort agreement between both methods on SPAP estimation was assessed through Bland-Altman analysis and at subject level, with Pearson's correlation coefficient. There was good agreement between the two methods (inter-method difference not significant (P > 0.05), bias ± standard deviation of - 0.1 ± 4.5 mmHg) independently of the degree of PAP, from baseline oxygen saturation levels to profound hypoxemia. At subject level, the median per-subject agreement was 0.7 ± 3.8 mmHg and Pearson's correlation coefficient 0.87 (P < 0.05). Our results demonstrate the feasibility of accurately assessing changes in SPAP by EIT in healthy volunteers. If confirmed in a patient population, the non-invasive and unsupervised day-to-day monitoring of SPAP could facilitate the clinical management of patients with pulmonary hypertension.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.