Evidence map›Paper›PMID 33293513›Full record

ArticleNature communications2020

Structure of native glycolipoprotein filaments in honeybee royal jelly.

Simone Mattei, Arvid Ban, Armin Picenoni, Marc Leibundgut, Rudi Glockshuber, Daniel Boehringer

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Exploratory proteomic characterization ofFrontiers in pharmacology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Theranostics · 2023
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 3 countries.

Simone MatteiDepartment of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, Otto-Stern-Weg 5, Zurich, 8093, Switzerland.ORCID 0000-0002-2005-8977
Arvid BanDepartment of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, Otto-Stern-Weg 5, Zurich, 8093, Switzerland.
Armin PicenoniDepartment of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, Otto-Stern-Weg 5, Zurich, 8093, Switzerland.
Marc LeibundgutDepartment of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, Otto-Stern-Weg 5, Zurich, 8093, Switzerland.
Rudi GlockshuberDepartment of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, Otto-Stern-Weg 5, Zurich, 8093, Switzerland. rudi@mol.biol.ethz.ch.ORCID 0000-0003-3320-3843
Daniel BoehringerDepartment of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, Otto-Stern-Weg 5, Zurich, 8093, Switzerland. boehringer@mol.biol.ethz.ch.ORCID 0000-0002-6666-8447
ETH Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Royal jelly (RJ) is produced by honeybees (Apis mellifera) as nutrition during larval development. The high viscosity of RJ originates from high concentrations of long lipoprotein filaments that include the glycosylated major royal jelly protein 1 (MRJP1), the small protein apisimin and insect lipids. Using cryo-electron microscopy we reveal the architecture and the composition of RJ filaments, in which the MRJP1 forms the outer shell of the assembly, surrounding stacked apisimin tetramers harbouring tightly packed lipids in the centre. The structural data rationalize the pH-dependent disassembly of RJ filaments in the gut of the larvae.

Indexed as

AnimalsBeesCryoelectron MicroscopyElectron Microscope TomographyFatty AcidsGlycoproteinsHydrogen-Ion ConcentrationInsect ProteinsLarvaLipoproteinsProtein MultimerizationRoyal JellyFatty AcidsGlycoproteinsInsect ProteinsLipoproteinsMRJP1 protein, Apis melliferaRoyal Jelly

Identifiers

PMID33293513
PMCPMC7722742
OpenAlexW3111611267

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.