Evidence map›Paper›PMID 33293480›Full record

ArticleMolecules and cells2020

NEUROD1 Intrinsically Initiates Differentiation of Induced Pluripotent Stem Cells into Neural Progenitor Cells.

Won-Young Choi, Ji-Hyun Hwang, Ann-Na Cho, Andrew J Lee, Inkyung Jung, Seung-Woo Cho, Lark Kyun Kim, Young-Joon Kim

Open access · diamondAbstract read
In one paragraph

Article in Molecules and cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

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  5. Rat embryonic stem cell-basedFrontiers in toxicology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Won-Young ChoiInterdisciplinary Program of Integrated OMICS for Biomedical Science, The Graduate School, Yonsei University, Seoul 03722, Korea.ORCID https://orcid.org/0000-0002-3576-5682
Ji-Hyun HwangInterdisciplinary Program of Integrated OMICS for Biomedical Science, The Graduate School, Yonsei University, Seoul 03722, Korea.ORCID https://orcid.org/0000-0001-6009-0632
Ann-Na ChoDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Korea.ORCID https://orcid.org/0000-0003-0047-8867
Andrew J LeeDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.ORCID https://orcid.org/0000-0001-9917-8834
Inkyung JungDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.ORCID https://orcid.org/0000-0002-5885-2754
Seung-Woo ChoDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Korea.ORCID https://orcid.org/0000-0001-8058-332X
Lark Kyun KimSeverance Biomedical Science Institute and BK21 PLUS Project for Medical Sciences, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, Korea.ORCID https://orcid.org/0000-0001-5983-4470
Young-Joon KimDepartment of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Korea.ORCID https://orcid.org/0000-0001-5061-587X
Yonsei University · KRKorea Advanced Institute of Science and Technology · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell type specification is a delicate biological event in which every step is under tight regulation. From a molecular point of view, cell fate commitment begins with chromatin alteration, which kickstarts lineage-determining factors to initiate a series of genes required for cell specification. Several important neuronal differentiation factors have been identified from ectopic over-expression studies. However, there is scarce information on which DNA regions are modified during induced pluripotent stem cell (iPSC) to neuronal progenitor cell (NPC) differentiation, the

Indexed as

Cell DifferentiationBasic Helix-Loop-Helix ProteinsChromatinEnhancer Elements, GeneticEpigenesis, GeneticHumansInduced Pluripotent Stem CellsNerve Tissue ProteinsNeural Stem CellsPromoter Regions, GeneticProtein BindingBasic Helix-Loop-Helix ProteinsChromatinNerve Tissue ProteinsNeurogenic differentiation factor 1chromatin accessibilityHi-Cinduced pluripotent stem cellNEUROD1neuronal progenitor cel

Identifiers

PMID33293480
PMCPMC7772509
OpenAlexW3111515387

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.