Evidence map›Paper›PMID 33293384›Full record

ArticlemBio2020

Essential Role for FtsL in Activation of Septal Peptidoglycan Synthesis.

Kyung-Tae Park, Shishen Du, Joe Lutkenhaus

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
4.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 75 citations in OpenAlex.

  1. Article
  2. Defining the order of assembly of theJournal of bacteriology · 2026
    Article
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  8. Defining the order of assembly of thebioRxiv : the preprint server for biology · 2026
    Article
  9. Article
  10. Article
  11. Peptidoglycan polymerase function and regulation.Microbiology and molecular biology reviews : MMBR · 2025
    Review
  12. FtsZ-mediated spatial-temporal control over septal cell wall synthesis.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  13. Control of morphogenesis during theScience advances · 2025
    Article
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Kyung-Tae ParkDepartment of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA.
Shishen DuDepartment of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA.
Joe LutkenhausDepartment of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, Kansas, USA jlutkenh@kumc.edu.
University of Kansas Medical Center · US

Funding

REGULATION OF CELL DIVISIONR37GM029764 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI LUTKENHAUS, JOSEPH F · 2000 to 2010
$4.8M
REGULATION OF EXPRESSION OF CELL DIVISION GENESR01GM029764 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI LUTKENHAUS, JOSEPH F · 1985 to 2022
$4.2M
NIGMS NIH HHS R01 GM029764NIGMS NIH HHS R37 GM029764
6 · The paper itself

Abstract

Spatiotemporal regulation of septal peptidoglycan (PG) synthesis is achieved by coupling assembly and activation of the synthetic enzymes (FtsWI) to the Z ring, a cytoskeletal element that is required for division in most bacteria. In

Indexed as

Bacterial ProteinsCell Cycle ProteinsCell DivisionEscherichia coliEscherichia coli ProteinsGene Expression Regulation, BacterialMembrane ProteinsMutationPeptidoglycanPhenotypeBacterial ProteinsCell Cycle ProteinsEscherichia coli ProteinsftsL protein, E coliFtsW protein, BacteriaMembrane ProteinsPeptidoglycancell divisiondivisomeseptal ringseptation

Identifiers

PMID33293384
PMCPMC7733951
OpenAlexW3112631654

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.