Evidence map›Paper›PMID 33293382›Full record

ArticlemBio2020

Comprehensive Genomic Investigation of Adaptive Mutations Driving the Low-Level Oxacillin Resistance Phenotype in Staphylococcus aureus.

Stefano G Giulieri, Romain Guérillot, Jason C Kwong, Ian R Monk, Ashleigh S Hayes, Diane Daniel, Sarah Baines, Norelle L Sherry, Natasha E Holmes, Peter Ward and 4 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
0.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 46 citations in OpenAlex.

  1. Mislocalization of PBPs inMicrobiology spectrum · 2026
    Article
  2. Article
  3. Methicillin-resistant Staphylococcus aureus.Nature reviews. Disease primers · 2026
    Review
  4. An Achilles' heel for methicillin-resistantAntimicrobial agents and chemotherapy · 2026
    Review
  5. Article
  6. Flies from meat processing facilities are carriers of multidrug-resistant Escherichia coli and diverse Staphylococcaceae species.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  7. Mutation of lipoprotein processing pathway geneAntimicrobial agents and chemotherapy · 2026
    Article
  8. Article
  9. Article
  10. Inactivation of KhpB (EloR/Jag) inApplied and environmental microbiology · 2025
    Article
  11. Article
  12. Article
  13. Review
  14. Genetic and Phenotypic Changes Related to the Development ofAntibiotics (Basel, Switzerland) · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Case Commentary: The hidden side of oxacillin resistance inAntimicrobial agents and chemotherapy · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Stefano G GiulieriDepartment of Microbiology and Immunology, The University of Melbourne at the Doherty Institute for Infection and Immunity, Melbourne, Australia.
Romain GuérillotDepartment of Microbiology and Immunology, The University of Melbourne at the Doherty Institute for Infection and Immunity, Melbourne, Australia.
Jason C KwongDepartment of Microbiology and Immunology, The University of Melbourne at the Doherty Institute for Infection and Immunity, Melbourne, Australia.
Ian R MonkDepartment of Microbiology and Immunology, The University of Melbourne at the Doherty Institute for Infection and Immunity, Melbourne, Australia.
Ashleigh S HayesDepartment of Microbiology and Immunology, The University of Melbourne at the Doherty Institute for Infection and Immunity, Melbourne, Australia.ORCID 0000-0003-2926-7561
Diane DanielDepartment of Microbiology and Immunology, The University of Melbourne at the Doherty Institute for Infection and Immunity, Melbourne, Australia.
Sarah BainesDepartment of Microbiology and Immunology, The University of Melbourne at the Doherty Institute for Infection and Immunity, Melbourne, Australia.ORCID 0000-0002-0557-0518
Norelle L SherryDepartment of Microbiology and Immunology, The University of Melbourne at the Doherty Institute for Infection and Immunity, Melbourne, Australia.
Natasha E HolmesDepartment of Infectious Diseases, Austin Health, Heidelberg, Australia.
Peter WardDepartment of Microbiology, Austin Health, Heidelberg, Australia.
Wei GaoDepartment of Microbiology and Immunology, The University of Melbourne at the Doherty Institute for Infection and Immunity, Melbourne, Australia.
Torsten SeemannDepartment of Microbiology and Immunology, The University of Melbourne at the Doherty Institute for Infection and Immunity, Melbourne, Australia.
Timothy P StinearDepartment of Microbiology and Immunology, The University of Melbourne at the Doherty Institute for Infection and Immunity, Melbourne, Australia.ORCID 0000-0003-0150-123X
Benjamin P HowdenDepartment of Microbiology and Immunology, The University of Melbourne at the Doherty Institute for Infection and Immunity, Melbourne, Australia bhowden@unimelb.edu.au.ORCID 0000-0003-0237-1473
The University of Melbourne · AUAustin Health · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antistaphylococcal penicillins such as oxacillin are the key antibiotics in the treatment of invasive methicillin-susceptible

Indexed as

Drug Resistance, BacterialMutationAdaptation, BiologicalAnti-Bacterial AgentsBacterial ProteinsGenome, BacterialGenomicsHumansMethicillin-Resistant Staphylococcus aureusOxacillinStaphylococcal InfectionsStaphylococcus aureusAnti-Bacterial AgentsBacterial ProteinsOxacillinantibiotic resistancegenomicsStaphylococcus aureusβ-lactams

Identifiers

PMID33293382
PMCPMC7733948
OpenAlexW3113122576

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.