Evidence map›Paper›PMID 33293313›Full record

Trial reportBMJ open2020

Relationship between acute pain trajectories after an emergency department visit and chronic pain: a Canadian prospective cohort study.

Raoul Daoust, Jean Paquet, Alexis Cournoyer, Éric Piette, Judy Morris, Justine Lessard, Gilles Lavigne, Jean-Marc Chauny

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02799004 (Opioid Prescription for Patient With Acute Pain After Discharge From Emergency Department), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02799004 completednot on this map

Opioid Prescription for Patient With Acute Pain After Discharge From Emergency Department: Ideal Duration for Adequate Relief, Adverse Events, and Addiction

TypeobservationalSponsorCentre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de MontrealRan2016 to 2018Enrolled761ConditionsAcute Pain
3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Trial
  2. Osteoclast-Derived SLIT3 Mediates Osteoarthritis Pain and Degenerative Changes.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Article
  4. Article
  5. Observational
  6. Observational
  7. Article
  8. Feelings of Patients Admitted to the Emergency Department.Healthcare (Basel, Switzerland) · 2025
    Article
  9. Article
  10. Sex bias in pain management decisions.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Physicians prescribe fewer analgesics during night shifts than day shifts.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Raoul DaoustEmergency, Hopital du Sacre-Coeur de Montreal Centre de Recherche, Montreal, Quebec, Canada raoul.daoust@videotron.ca.ORCID 0000-0001-6507-0198
Jean PaquetEmergency, Hopital du Sacre-Coeur de Montreal Centre de Recherche, Montreal, Quebec, Canada.
Alexis CournoyerFaculte de medecine, Université de Montréal, Montréal, Quebec, Canada.
Éric PietteFaculte de medecine, Université de Montréal, Montréal, Quebec, Canada.
Judy MorrisDepartment of Emergency Medicine, Hopital du Sacre-Coeur de Montreal, Montréal, Quebec, Canada.
Justine LessardEmergency, Hopital du Sacre-Coeur de Montreal Centre de Recherche, Montreal, Quebec, Canada.
Gilles LavigneMédecine Dentaire, Université de Montréal, Montreal, Quebec, Canada.
Jean-Marc ChaunyDepartment of Emergency Medicine, Hopital du Sacre-Coeur de Montreal, Montréal, Quebec, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesInadequate acute pain management can reduce the quality of life, cause unnecessary suffering and can often lead to the development of chronic pain. Using group-based trajectory modelling, we previously identified six distinct pain intensity trajectories for the first 14-day postemergency department (ED) discharge; two linear ones with moderate or severe pain during follow-up (~40% of the patients) and four cubic polynomial order trajectories with mild or no pain at the end of the 14 days (low final pain trajectories). We assessed if previously described acute pain intensity trajectories over 14 days after ED discharge are predictive of chronic pain 3 months later.

designProspective cohort study.

settingTertiary care trauma centre academic hospital.

participantsThis study included 18 years and older ED patients who consulted for acute (≤2 weeks) pain conditions that were discharged with an opioid prescription. Patients completed a 14-day diary in which they listed their daily pain intensity (0-10 numeric rating scale). OUTCOMES: Three months after ED visit, participants were questioned by phone about their current pain intensity (0-10 numeric rating scale). Chronic pain was defined as patients with current pain intensity ≥4 at 3 months.

resultsA total of 305 participants remained in the study at 3 months, 49% were women and a mean age of 55±15 years. Twelve per cent (11.9; 95% CI 8.2 to 15.4) of patients had chronic pain at the 3-month follow-up. Controlling for age, sex and pain condition, patients with moderate or severe pain trajectories and those with only a severe pain trajectory were respectively 5.1 (95% CI 2.2 to 11.8) and 8.2 (95% CI 3.4 to 20.0) times more likely to develop chronic pain 3 months later compared with patients in the low final pain trajectories.

conclusionSpecific acute pain trajectories following an ED visit are closely related to the development of chronic pain 3 months later. TRIAL REGISTRATION NUMBER: NCT02799004; Results.

Indexed as

Acute PainChronic PainAdultAgedCanadaEmergency Service, HospitalFemaleHumansMaleMiddle AgedProspective StudiesQuality of Lifeaccident & emergency medicinepain managementtrauma management

Identifiers

PMID33293313
PMCPMC7722811

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.